FODMAP Diet for Pelvic Endometriosis With GI Symptoms

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares a structured FODMAP dietary regimen to a standard treatment plan without specific dietary guidance in women with surgically or diagnostically confirmed endometriosis and irritable bowel-like symptoms. The aim is to see if reducing certain fermentable carbohydrates lessens pelvic pain and related symptoms. Participants are 18 to 45 years old, with a BMI between 18.5 and 24.9, and are either on hormonal therapy or not. The trial is led by Fondazione IRCCS Ca' Granda and is based in Milan, Italy. Outcomes focus on pain, quality of life, and sexual function, reflecting a holistic view of endometriosis impact.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age between 18 and 45 years
* BMI between 18.5 and 24.9,
* Surgical, clinical or instrumental diagnosis of endometriosis
* Presence of bowel symptoms (i.e., bloating, nausea, constipation, diarrhea, and vomiting) referable to irritable bowel syndrome, on estro-progestin or progestin treatment or in the absence of hormonal treatment

Exclusion Criteria:

* Associated conditions that may cause pelvic pain independent of the presence of endometriosis (e.g., pelvic varices and salpingitis outcomes)
* chronic inflammatory bowel disease (Crohn's disease or ulcerative rectocolitis).
* patients with obstructive uropathy, subocclusive intestinal stenosis
* complex adnexal masses or typical endometriomas greater than 5 cm in diameter.
* women who are obese (BMI ≥ 30) or underweight (BMI \< 18)
* women on vegetarian-vegan dietary regimens,
* women with metabolic diseases that require specific dietary indications such as in the case of diabetes and celiac disease.

Where it's running

• Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
  Milan, Italy Recruiting

Study contacts

• Study coordinator: Giussy Barbara
• Email: giussy.barbara@policlinico.mi.it
• Phone: +393471753089

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.