Flow-Controlled vs Volume-Controlled Ventilation in Lumbar Disc Herniation Surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective randomized trial compares two ventilation modes—flow-controlled ventilation (FCV) and volume-controlled ventilation (VCV)—in adults undergoing lumbar disc herniation surgery under general anesthesia. Ventilation parameters and oxygenation metrics are collected at predefined times after intubation, with the primary endpoint being arterial PaO2 after 20 minutes in the prone position. Eligible participants are 18–65 years old, ASA I–III, and BMI 18–30 kg/m². The study aims to inform whether FCV offers hemodynamic or respiratory advantages over VCV during this specific surgical setting.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age between 18 and 65 years
* ASA physical status I-III
* Body Mass Index between 18 and 30 kg/m²

Exclusion Criteria:

* Age \< 18 years or \> 65 years
* Known or previously diagnosed pulmonary disease
* Patients with severe preoperative pulmonary function impairment (e.g., FEV₁ \< 50% predicted, severe restrictive or obstructive pathology)
* Patients with markedly altered lung anatomy or function due to prior major thoracic surgery
* Patients who were dependent on supplemental oxygen therapy in the preoperative period
* ASA physical status IV or higher
* Refusal or inability to provide informed consent

Where it's running

• Ankara Etlik City Hospital
  Ankara, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Atakan Sezgi
• Email: kansezgi@gmail.com
• Phone: 00905323327000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.