FCV vs VC—Obese Adults Undergoing Laparoscopic Surgery
Official title: Comparison of VC-AF and FCV Mechanical Ventilation Modes in Obese Patients Undergoing Laparoscopic Surgery
Run by Kocaeli University · NCT07875530 · Data updated 2026-11-12
In obese adults having laparoscopic surgery, researchers will see if flow-controlled ventilation (FCV) works better than volume-controlled ventilation with autoflow (VC-AF) at keeping airway pressures and lung energy lower.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 78 (estimated) |
| Sponsor | Kocaeli University Academic / other |
| Locations | 1 site (Kocaeli, Izmit) |
| Status | Recruiting |
| Started | September 21, 2026 |
| Main results expected | June 21, 2027 |
| Study ends | September 21, 2027 |
| Registry record updated | October 15, 2026 |
| Trial ID | NCT07875530 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (≥18) with BMI ≥30 scheduled for elective laparoscopic surgery under general anesthesia, ASA I–III, without COPD or pacemakers.
✕Probably not a fit
Patients with other conditions or settings where FCV does not reduce respiratory stress may not see a benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study compares two ventilation strategies, FCV and VC-AF, in adults with BMI 30 or higher undergoing elective laparoscopic procedures under general anesthesia. It focuses on airway pressures, driving pressure, and the mechanical power delivered to the lungs to see if FCV can reduce potential lung stress during pneumoperitoneum. The investigation leverages existing perioperative data to explore differences in respiratory mechanics between the two ventilation modes. The study is conducted at Kocaeli University, enrolling adult patients without known COPD or pacemakers and excluding pregnancy and emergency surgeries. The goal is to better understand how ventilation choices may influence the risk of ventilator-associated lung injury in obese surgical patients.
Why it matters
Potential benefit: If FCV lowers airway pressures and mechanical power, it could reduce lung stress and potential lung injury during surgery for obese patients.
How similar studies have gone: Previous work suggests that ventilation strategy can impact respiratory mechanics; this study applies FCV in an obese surgical population, where data are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Age ≥18 years Body mass index (BMI) ≥30 kg/m² American Society of Anesthesiologists (ASA) Physical Status I-III Scheduled to undergo elective laparoscopic surgery under general anesthesia Exclusion Criteria: Pregnancy Emergency surgery Presence of a cardiac pacemaker Chronic obstructive pulmonary disease (COPD)
Where it's running
-
Kocaeli University Faculty of Medicine
Kocaeli, Izmit, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Elif Balcı Koç, MD
- Email: elfblc67@gmail.com
- Phone: +90 543 487 10 38
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.