Factors influencing treatment outcomes in colorectal cancer patients
Factors Affecting the Results of Treatment of Patients With Colorectal Cancer
This study looks at how different factors, like where the tumor is located, affect recovery and survival in colorectal cancer patients after surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1200 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Immanuel Kant Baltic Federal University Academic / other |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Kaliningrad, Kaliningrad Oblast) |
| Trial ID | NCT06050447 on ClinicalTrials.gov |
What this trial studies
This observational study aims to quantify the risks associated with mortality, anastomotic leakage, and other postoperative complications in patients undergoing surgery for colorectal cancer. It will analyze how the localization of the tumor affects recurrence rates and cancer-specific survival. The study will involve various surgical interventions, including hemicolectomy and rectal resections, to gather comprehensive data on patient outcomes. By assessing these factors, the study seeks to improve understanding of treatment efficacy in colorectal cancer.
Who should consider this trial
Good fit: Ideal candidates include patients with histologically confirmed primary adenocarcinoma of the bowel who are eligible for surgical treatment.
Not a fit: Patients with unresectable tumors or those requiring preoperative chemotherapy or radiation therapy may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical strategies and better patient outcomes in colorectal cancer treatment.
How similar studies have performed: While similar studies have explored postoperative outcomes in colorectal cancer, this specific approach focusing on tumor localization and its impact on treatment results is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Histologically proven primary adenocarcinoma of bowel; * All patients who have indications for surgical treatment of colorectal cancer based on the decision of the oncological council; * Signed informed consent with agreement to attend all study visits; Exclusion Criteria: * Unresectable tumor or contradictions to surgery; * Indications for chemotherapy or radiation therapy prior to surgery; * Patient withdrawal from the trial or loss of follow-up; * Emergent operation; * Pregnancy.
Where this trial is running
Kaliningrad, Kaliningrad Oblast
- Baltic Federal University — Kaliningrad, Kaliningrad Oblast, Russia (Recruiting)
Study contacts
- Principal investigator: Mikhail A Agapov, PhD — Baltic Federal University
- Study coordinator: Tatiana N Garmanova, PhD
- Email: tatianagarmanova@gmail.com
- Phone: +79773429249
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.