Photon-counting CT vs conventional CT for carotid plaque in people with carotid artery stenosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective observational study comparing photon-counting detector CT angiography (PCD-CTA) with conventional energy-integrating detector CTA (EID-CTA) for assessing carotid atherosclerotic plaques in patients with carotid artery stenosis. Researchers will analyze differences in visualization, plaque morphology, plaque burden, components, calcification artifacts, and the degree of stenosis, alongside objective and subjective image quality. The goal is to determine if PCD-CTA’s higher spatial resolution and spectral imaging offer advantages over conventional CT for carotid disease characterization. No interventions are randomized or assigned; imaging findings from both methods will be contrasted to identify potential benefits.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 years or older.
* Patients with carotid atherosclerotic plaque or carotid artery stenosis.
* Patients scheduled to undergo carotid artery stenting.
* Patients undergoing preprocedural carotid CTA examination.
* Ability to provide written informed consent.

Exclusion Criteria:

* Known allergy to iodinated contrast material.
* Severe renal insufficiency or other contraindications to contrast-enhanced CT.
* Pregnancy or suspected pregnancy.
* Severe motion or other artifacts resulting in nondiagnostic image quality.
* Incomplete clinical or imaging data.

Where it's running

• Chinese PLA General Hospital
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Study coordinator: Jinhao Lyu, MD
• Email: 330322990@qq.com
• Phone: +8615903562929

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.