Exploring how coffee affects metabolic rate

Variation in the Impact of Coffee on the Metabolic Rate

NA · Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences · NCT06432504

This study tests how drinking coffee affects metabolism in healthy adults by looking at different doses of caffeine and how factors like age and body type play a role.

Quick facts

PhaseNA
Study typeInterventional
Enrollment100 (estimated)
Ages18 Years to 40 Years
SexAll
SponsorShenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences (other)
Locations1 site (Shenzhen, Guangdong)
Trial IDNCT06432504 on ClinicalTrials.gov

What this trial studies

This study investigates how coffee consumption influences metabolic rate in healthy adults, focusing on variations based on age, sex, body composition, and habitual coffee intake. Participants will be randomly assigned to receive different doses of caffeine and undergo metabolic measurements before and after consumption. The study will also analyze genetic factors by collecting blood samples for SNP analysis. Participants must refrain from strenuous exercise prior to the experiment to ensure accurate results.

Who should consider this trial

Good fit: Ideal candidates are healthy adults aged 18-40 who do not have any metabolic or digestive diseases.

Not a fit: Patients with recent surgeries, long-term medication needs, or metabolic diseases will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into how coffee consumption affects metabolism, potentially guiding dietary recommendations.

How similar studies have performed: While studies on caffeine and metabolism exist, this specific investigation into individual variations based on genetic and demographic factors is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Healthy adults 18-40 years old

Exclusion Criteria:

Those who have undergone surgery in the past 6 months. People are requiring long-term medication. People have metabolic diseases, like diabetes, hypoglycemia, gout, osteoporosis, etc.

People have digestive diseases, like gastric ulcer, pancreatitis, intestinal obstruction, etc.

Those who have recently lost weight for various medical reasons ( like cancer, etc.).

People are suffering from infectious diseases ( like HIV, etc.). People have blood phobia, pathological hypo or hyper tension. People with impaired glucose tolerance. Those who are afflicted with claustrophobia.

Where this trial is running

Shenzhen, Guangdong

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Healthy, Coffee, Caffeine, Metabolic rate, Caffeine clearance

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.