Exploring end-stage liver disease in China

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the current situation of end-stage liver disease in China, focusing on the optimization of diagnosis and treatment. It will analyze various forms of liver cirrhosis, including those caused by hepatitis and alcohol, and their associated complications such as portal hypertension and hepatic encephalopathy. The study is single-center and prospective, gathering real-world data to standardize treatment approaches for liver cirrhosis and its complications. By understanding the epidemiological landscape, the study seeks to inform better empirical treatment plans for patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Informed consent of patients.
2. Diagnosis of any of the following diseases: acute decompensation of cirrhosis, chronic and acute liver failure, chronic liver failure and hepatocellular carcinoma (stage III-IV)

Exclusion Criteria:

1. HIV antibody positive and AIDS patients
2. Serious psychiatric history, especially depression. Severe mental illness is defined as major depression or psychosis, suicide attempts, hospitalization due to mental illness or a period of disability due to mental illness.
3. Patients with serious diseases of heart, lung, kidney, brain, blood and other important organs.
4. Patients with other malignant tumors (excluding those cured).
5. Pregnant, lactating women or women of childbearing age who are ready to conceive.

Where it's running

• HuaShan Hospital
  Shanghai, Shanghai Municipality, China Recruiting

Study contacts

• Study coordinator: Jingwen Ai, Doctor
• Email: JINGWENAI1990@126.COM
• Phone: 13764990804

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Even protein distribution plus exercise for people awaiting liver transplant

  This trial tests whether spreading daily protein evenly and combining it with a 12-week exercise program improves nutrition, muscle mass, and function in people waiting for a liver transplant compared with uneven protein timing or usual advice.

  Recruiting at 2 sites Agricultural University of Athens · Athens, Attica and 1 other locations · NCT07561138

• Preoperative Carbohydrate Loading Before Liver Transplant

  This study tests whether drinking a carbohydrate beverage before anesthesia helps liver transplant patients recover faster.

  Recruiting Medical University of Warsaw · Warsaw · NCT07519057

• Frailty, Nutrition, and Recovery in People Waiting for a Liver Transplant

  This project will test whether measures of frailty, muscle loss, nutrition, and psychological health can predict outcomes for adults (18–65) on the liver transplant waiting list in Turkey.

  Recruiting Izmir Bakircay University · Izmir · NCT07414095

• Train the immune system to accept a living-donor liver so you may stop lifelong anti-rejection drugs

  This test gives donor stem cells plus a short conditioning treatment to people with HLA-matched living-donor liver transplants to see if they can safely stop long-term immunosuppressive drugs.

  Recruiting Phase 1/2 University of California, Los Angeles · Los Angeles, California · NCT07269041

• Risks of lung-opening maneuvers and PEEP adjustments in ventilated children

  This project will track how often lung-opening maneuvers and PEEP adjustments cause complications in children under 14 who are on mechanical ventilation in the PICU.

  Recruiting Hospital de Alta Complejidad en Red · Canuelas, Buenos Aires · NCT07233304

• Assessing frailty in older patients undergoing digestive endoscopy

  This study is trying to see how frailty affects older patients over 70 who are having digestive endoscopy and whether it impacts their safety and the success of the procedure.

  Recruiting Parc de Salut Mar · Barcelona · NCT06507527

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.