Exercise program to improve cognition in older Veterans
Relationship of Exercise Frequency, Intensity, and Fitness to Improved Cognition and Biomarkers in Gerofit Participants
This study is testing whether an exercise program can help improve thinking skills in older Veterans who may be dealing with memory problems or other health issues.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 150 (estimated) |
| Ages | 65 Years and up |
| Sex | All |
| Sponsor | VA Office of Research and Development Federal |
| Locations | 2 sites (West Los Angeles, California and 1 other locations) |
| Trial ID | NCT06107842 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of the Gerofit exercise program on cognitive function in Veterans aged 65 and older. It aims to address the high prevalence of cognitive impairment and dementia among older Veterans, particularly those with comorbid conditions such as PTSD and depression. By incorporating physical activity and health education, the study seeks to enhance both physical and cognitive health outcomes. The research will also explore the predictive power of biomarkers related to exercise and cognition.
Who should consider this trial
Good fit: Ideal candidates for this study are Veterans aged 65 and older who are eligible for the VA Gerofit program and have received clearance from their primary care provider.
Not a fit: Patients who are unable to perform activities of daily living or have significant cognitive impairment may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly improve the cognitive function and overall quality of life for older Veterans.
How similar studies have performed: Other studies have shown positive outcomes with exercise interventions in older adults, suggesting potential success for this approach in Veterans.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All Veterans eligible for VA Gerofit program 65 years and older * Clearance by PCP to participate in Gerofit exercise program Exclusion Criteria: * Inability to perform ADLs * Significant cognitive impairment * Inability to function independently without assistance * Unstable angina; proliferative diabetic retinopathy * Oxygen dependent * Unwillingly to commute and/or not able to provide own transportation to Gerofit * Incontinence * Open wounds * Volatile behavioral issue or unable to work successfully in a group environment/setting * Active substance abuse * Homelessness
Where this trial is running
West Los Angeles, California and 1 other locations
- VA Greater Los Angeles Healthcare System, West Los Angeles, CA — West Los Angeles, California, United States (Recruiting)
- Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD — Baltimore, Maryland, United States (Recruiting)
Study contacts
- Principal investigator: Cathy C Lee, MD — VA Greater Los Angeles Healthcare System, West Los Angeles, CA
- Study coordinator: Cathy C Lee, MD
- Email: cathy.lee2@va.gov
- Phone: (310) 268-4110
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.