Screening for heart failure in older adults with atrial fibrillation in rural China

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational cohort study enrolling at least 2,500 rural-dwelling adults aged 65–80 with confirmed atrial fibrillation. Participants will undergo heart failure screening using NT-proBNP testing and echocardiography, with additional data collection on ECG signals, seismocardiography, voice, and demographics. After enrollment, participants will be followed every three months to monitor the incidence and progression of heart failure and related cardiovascular events. The study aims to characterize HF burden and progression in this population and to establish longitudinal data for risk stratification. The interventions are observational and data-driven rather than therapeutic, conducted at Jiangsu Taizhou People’s Hospital in Taizhou, Jiangsu.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Permanent residents with local household registration in rural China.
2. Aged 65-80 years.
3. Electrocardiogram confirmation of AF or possession of a diagnostic certificate for AF issued by a specialist.
4. Willing to participate in HF screening.
5. Ability to understand the study procedures and provide written informed consent.

Exclusion Criteria:

1. Expected life expectancy of less than 3 months.
2. Severe renal insufficiency (Ccr \< 30ml/min) or ongoing dialysis treatment.
3. Cardiac insufficiency secondary to correctable causes, including hyperthyroid heart disease, anemic heart disease, or uncorrected congenital heart disease.
4. Indications for pacemaker implantation without having undergone implantation.
5. Chronic obstructive pulmonary disease complicated by type II respiratory failure.
6. Special populations, including patients with mental illnesses.

Where it's running

• Department of Cardiology
  Taizhou, Jiangsu, China Recruiting

Study contacts

• Study coordinator: Chuanmeng Zhang, Dr.
• Email: tzyyzcm@njmu.edu.cn
• Phone: +8615996000626

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.