Evaluation of patients with mood and anxiety disorders and healthy volunteers
Official title: The Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers
Run by National Institutes of Health Clinical Center (CC) · NCT00024635 · Data updated 2026-11-12
This study is looking for people with mood and anxiety disorders, as well as healthy volunteers, to see if they can help with research that aims to better understand these conditions.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 3 Years to 99 Years |
| Sex | All |
| Enrollment | 16000 (estimated) |
| Sponsor | National Institutes of Health Clinical Center (CC) NIH |
| Locations | 1 site (Bethesda, Maryland) |
| Status | Recruiting |
| Started | February 2, 2001 |
| Registry record updated | October 2, 2026 |
| Trial ID | NCT00024635 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals aged 3 to 99 with mood or anxiety disorders, as well as healthy volunteers.
✕Probably not a fit
Patients with current alcohol or substance use or dependence may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This protocol aims to screen patients with mood and anxiety disorders, as well as healthy volunteers, for participation in research at the National Institute of Mental Health (NIMH). Participants will undergo a comprehensive evaluation that includes psychiatric interviews, diagnostic assessments, medical histories, physical exams, and various laboratory tests. The collected data will help enhance understanding of mood disorders and may link to other research protocols for deeper insights into diagnosis and treatment responses. The study serves as an entry point for individuals interested in participating in NIMH-approved research.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and treatment options for mood and anxiety disorders.
How similar studies have gone: Other studies focusing on mood and anxiety disorders have shown success in enhancing understanding and treatment, making this approach both relevant and tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
* INCLUSION CRITERIA: * Subjects ages 3 to 99 may enroll in the protocol. * Subjects must be competent to comprehend the purpose of the screening process and to provide written informed consent and be willing to participate in NIMH IRB approved research protocols. Minors will be asked to assent and their parents will sign the consent form. EXCLUSION CRITERIA: -Current alcohol or substance use or dependence (excluding nicotine) within the past 3 months of sufficient magnitude to require independent, concurrent treatment intervention (e.g. Antabuse or opiate treatment, but not including self-help groups).
Where it's running
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National Institutes of Health Clinical Center
Bethesda, Maryland, United States Recruiting
Study contacts
- Principal investigator: Carlos A Zarate, M.D. — National Institute of Mental Health (NIMH)
- Study coordinator: Carlos A Zarate, M.D.
- Email: moodresearch@mail.nih.gov
- Phone: (877) 646-3644
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Neuro-computational look at mood fluctuations in depression and bipolar disorder.
This tests whether combining brain scans, cognitive tests, and daily smartphone mood tracking can model and help predict mood changes in people with depression or bipolar disorder.
-
Using RxWell to Reduce Opioid Use After Knee or Hip Surgery
This study is testing whether a digital tool called RxWell can help people with mood disorders who are having knee or hip surgery reduce their opioid use and improve their mental health after the operation.
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Preventive behavioral intervention for young adults with psychotic experiences
This study is testing if a new Resilience Training program can help college freshmen and sophomores who are at risk for serious mental illnesses feel better and prevent issues like psychosis, mood swings, and anxiety.
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Brain stimulation for anxiety and depression in children and teens
This program will try transcranial magnetic stimulation (TMS) to see if it reduces anxiety and depression in children and teens aged 6 to 18 who are referred by their doctors.
-
Evaluating mentalization-based psychotherapy for anxiety and depression
This study is testing a new group therapy called mentalization-based psychotherapy to see if it helps people with anxiety and depression feel better compared to standard therapy.
-
Cognitive Behavioural Therapy for youth with mood and anxiety disorders
This study is testing a new type of Cognitive Behavioural Therapy called CBT-MyOWL for young people aged 14-19 with mood and anxiety disorders to see if it helps them stick with treatment and feel better compared to standard therapy.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.