Evaluating oxygen levels in colon vascular lesions
Official title: Oxygenation in Vascular Lesions of the Colon
Run by University of Chicago · NCT06230731 · Data updated 2026-11-12
This study is trying to see if the oxygen levels in the colon of people with certain blood vessel problems are different from those in healthy individuals.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 89 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | University of Chicago Academic / other |
| Locations | 1 site (Chicago, Illinois) |
| Status | Recruiting |
| Started | February 1, 2024 |
| Main results expected | February 1, 2027 |
| Study ends | February 1, 2029 |
| Registry record updated | July 9, 2026 |
| Trial ID | NCT06230731 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals aged 18 to 89 with a history of vascular lesions in the colon or those with a healthy colon.
✕Probably not a fit
Patients under 18 years, over 90 years, or those with specific colon ulcerations or previous colon surgeries may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial aims to assess the oxygenation levels in the colon of individuals with acquired vascular abnormalities, such as angiodysplasia and AVMs, compared to healthy controls. The study focuses on understanding the potential link between chronic hypoxia and the development of these vascular lesions, which can lead to significant gastrointestinal bleeding and anemia. Participants will undergo standard colonoscopy procedures to evaluate their condition and oxygen saturation levels in the colon.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of vascular lesions in the colon, potentially reducing complications like bleeding and anemia.
How similar studies have gone: While the specific approach of evaluating oxygenation in vascular lesions is novel, related studies on vascular abnormalities have shown varying degrees of success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Undergo standard of care colonoscopy * People with a history of vascular lesions of the colon * People with healthy colon * 18 - 89 years of age Exclusion Criteria: * Age \< 18 years * Age \> 90 years * People with ulcerations in at ascending colon opposite the ileocecal valve * Previous colon surgery
Where it's running
-
University of Chicago
Chicago, Illinois, United States Recruiting
Study contacts
- Principal investigator: Joel Pekow, MD — University of Chicago
- Study coordinator: Joel Pekow, MD
- Email: jpekow@bsd.uchicago.edu
- Phone: (773) 834-8632
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.