Evaluating oxygen levels in colon vascular lesions
Oxygenation in Vascular Lesions of the Colon
This study is trying to see if the oxygen levels in the colon of people with certain blood vessel problems are different from those in healthy individuals.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years to 89 Years |
| Sex | All |
| Sponsor | University of Chicago Academic / other |
| Locations | 1 site (Chicago, Illinois) |
| Trial ID | NCT06230731 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to assess the oxygenation levels in the colon of individuals with acquired vascular abnormalities, such as angiodysplasia and AVMs, compared to healthy controls. The study focuses on understanding the potential link between chronic hypoxia and the development of these vascular lesions, which can lead to significant gastrointestinal bleeding and anemia. Participants will undergo standard colonoscopy procedures to evaluate their condition and oxygen saturation levels in the colon.
Who should consider this trial
Good fit: Ideal candidates include individuals aged 18 to 89 with a history of vascular lesions in the colon or those with a healthy colon.
Not a fit: Patients under 18 years, over 90 years, or those with specific colon ulcerations or previous colon surgeries may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of vascular lesions in the colon, potentially reducing complications like bleeding and anemia.
How similar studies have performed: While the specific approach of evaluating oxygenation in vascular lesions is novel, related studies on vascular abnormalities have shown varying degrees of success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Undergo standard of care colonoscopy * People with a history of vascular lesions of the colon * People with healthy colon * 18 - 89 years of age Exclusion Criteria: * Age \< 18 years * Age \> 90 years * People with ulcerations in at ascending colon opposite the ileocecal valve * Previous colon surgery
Where this trial is running
Chicago, Illinois
- University of Chicago — Chicago, Illinois, United States (Recruiting)
Study contacts
- Principal investigator: Joel Pekow, MD — University of Chicago
- Study coordinator: Joel Pekow, MD
- Email: jpekow@bsd.uchicago.edu
- Phone: (773) 834-8632
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.