Clinical trial No longer in our active list Observational Ages 18 and up Women only

Evaluating muscle strength and function in women with lipedema

Official title: Muscle Strength, Muscle Endurance, Lower Extremity Function, Aerobic Capacity, Pressure Pain Threshold and Edema in Women with Lipedema: a Case-Control Study

Run by Gazi University · NCT06866847 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study is testing how lipedema affects muscle strength and physical abilities in women by comparing them to healthy women.

Quick facts

Study typeObservational
Ages18 Years and up
SexWomen only
Enrollment30 (estimated)
SponsorGazi University
Academic / other
Locations1 site (Ankara)
Trial IDNCT06866847 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are women aged 18 and older who have been diagnosed with lipedema.

Probably not a fit

Patients with cardiovascular, orthopedic, or neurological issues that could affect their physical capacity may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess various physical parameters in women diagnosed with lipedema, a condition characterized by painful, disproportionate fat distribution in the extremities. The study will compare muscle strength, endurance, lower extremity function, aerobic capacity, pressure pain threshold, and edema between women with lipedema and a control group of healthy women. Participants will undergo specific tests to measure these parameters, providing valuable insights into the impact of lipedema on physical capabilities. The findings may help in understanding the condition better and guiding future interventions.

Why it matters

Potential benefit: If successful, this study could enhance the understanding of lipedema and lead to improved management strategies for affected patients.

How similar studies have gone: While there is limited research specifically on lipedema, similar studies on related conditions have shown promising results in understanding physical impairments.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Women over the age of 18 diagnosed with lipedema

Exclusion Criteria:

* Having cardiovascular, orthopedic and/or neurological problems that may affect physical capacity

  * Having diseases such as heart failure, kidney failure that may cause general or localized edema

Where it's running

  • Gazi University Faculty of Health Sciences
    Ankara, Turkey
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Kinesio Taping Added to Standard Care for Women with Lipedema

    This study tests whether adding kinesio taping to usual care helps reduce pain for women with stage II lipedema.

    Recruiting Kanuni Sultan Suleyman Training and Research Hospital · Küçükçekmece, Istanbul · NCT07919574

  • Comparison of body composition in lipedema and obesity

    This study tests whether women with lipedema have different segmental body fat and muscle distribution compared with BMI-matched women without lipedema.

    Recruiting Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey · Istanbul, Uskudar · NCT07878299

  • Comparison of Different Exercise Protocols for Lipedema

    This study tests whether high‑intensity interval training or moderate‑intensity continuous training improves function, strength, and quality of life in adults with lipedema.

    Recruiting Hitit University · Çorum · NCT07873541

  • taVNS-enriched rehab for lipedema

    This study tests whether adding transcutaneous auricular vagus nerve stimulation (taVNS) to standard rehabilitation helps people with lipedema reduce symptoms.

    Recruiting Istanbul University - Cerrahpasa · Istanbul, Eyupsultan · NCT07857499

  • Manual and self-lymphatic drainage with exercise for lipedema

    This study tests whether manual lymph drainage plus supervised exercise works better than self-lymph drainage plus guided activity for reducing pain and improving function in women with lipedema over six weeks.

    Recruiting Istanbul University - Cerrahpasa · Istanbul, Eyupsultan · NCT07803926

  • Turkish version of the Duke Activity Status Index in women with lipedema

    This study tests whether the Turkish Duke Activity Status Index accurately and consistently measures functional capacity in women with lipedema.

    Recruiting Istanbul University - Cerrahpasa · Istanbul, Eyupsultan · NCT07803913

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.