Evaluating healing and comfort after gum graft procedures using special adhesives

Effect of Cyanoacrylate and Concentrated Growth Factor on Wound Healing and Patient Comfort at the Palatal Donor Site

Not applicable Interventional Yuzuncu Yıl University · NCT06459947

This study is testing whether special adhesives can help people heal better and feel less pain after gum graft surgeries.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years to 55 Years
SexAll
SponsorYuzuncu Yıl University Academic / other
Locations1 site (Van)
Trial IDNCT06459947 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to assess the recovery and pain levels at the palatal donor site following free gingival graft (FGG) surgeries. It will compare the effects of cyanoacrylate tissue adhesives and concentrated growth factor (CGF) on wound healing and patient comfort. The study will involve a randomized controlled design to ensure reliable results, focusing on the morbidity associated with the donor area. By isolating the wound from the oral environment and utilizing advanced healing techniques, the study seeks to improve patient outcomes.

Who should consider this trial

Good fit: Ideal candidates are systemically healthy individuals who have not undergone periodontal surgery in the last six months.

Not a fit: Patients who smoke, have medication allergies, or experience high anxiety may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance healing and reduce discomfort for patients undergoing gum graft procedures.

How similar studies have performed: Other studies have shown promising results with the use of cyanoacrylate and platelet concentrates in enhancing wound healing, suggesting this approach may be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* systemically healthy
* not had periodontal surgery in the last 6 months

Exclusion Criteria:

* smoker
* allergic to medication
* high anxiety (using modified dental anxiety scale)

Where this trial is running

Van

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Wound HealingPainPatient Comfortcyanoacrylatefree gingival graftconcentrated growth factor
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.