Evaluating external biliary drainage in living donor liver transplantation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to assess the incidence of biliary complications following living donor liver transplantation (LDLT) by comparing two groups: one receiving external biliary drainage (EBD) and the other undergoing conventional duct-to-duct anastomosis without EBD. Patients aged 18 and older who are eligible for LDLT will be randomly assigned to either group in a 1:1 ratio. The primary outcome will measure the rate of biliary complications one year post-transplant. This prospective approach seeks to determine if EBD can effectively reduce complications associated with LDLT.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Living donor liver transplantation
* Adult patient (\>=18 years old)
* Patients who are available for at least 3 year follow-up after LDLT

Exclusion Criteria:

* Patients requring hepaticojejunostomy due to anatomical factor or underlying disease
* Re-transplantation
* Multiorgan transplantation
* Emergency transplantation

Where it's running

• Seoul National University Hospital
  Seoul, South Korea Recruiting

Study contacts

• Study coordinator: Su young Hong, MD
• Email: sypurple@gmail.com
• Phone: +82-2-2072-2326

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Preoperative Carbohydrate Loading Before Liver Transplant

  This study tests whether drinking a carbohydrate beverage before anesthesia helps liver transplant patients recover faster.

  Recruiting Medical University of Warsaw · Warsaw · NCT07519057

• Expanding HIV-positive donor livers for HIV-positive recipients

  This study tests whether liver transplants from HIV-positive donors to HIV-positive recipients are safe regarding opportunistic infections and cancer.

  Recruiting at 2 sites National Institute of Allergy and Infectious Diseases (NIAID) · Baltimore, Maryland and 1 other locations · NCT07778459

• Everolimus-based calcineurin-free immunosuppression one year after liver transplant

  This trial tests whether switching to or using everolimus with reduced calcineurin inhibitors after year one post-liver transplant can protect kidney function while maintaining graft health in adults at low rejection risk.

  Recruiting Phase 3 Hannover Medical School · Heidelberg, Baden-Wurttemberg and 15 other locations · NCT07739914

• Magnetic Resonance Cholangiopancreatography to help living liver donors and their recipients

  This study tests whether preoperative MRCP imaging can help select living liver donors and reduce biliary complications in recipients.

  Recruiting Institute of Liver and Biliary Sciences, India · New Delhi · NCT07715500

• Sleep quality and its determinants during the liver transplant pathway

  This study tests how sleep quality changes from before liver transplantation to six months after, in adults on the transplant waitlist at a single hospital.

  Recruiting Hospices Civils de Lyon · Lyon · NCT07674355

• Preoperative CIMT and Intraoperative Hemodynamics in Liver Transplant

  This study looks at whether a higher carotid IMT measured before surgery is linked to more unstable blood pressure during liver transplant.

  Recruiting Dicle University · Diyarbakır · NCT07660679

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.