Preoperative CIMT and Intraoperative Hemodynamics in Liver Transplant

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This retrospective observational study analyzes whether preoperative carotid intima-media thickness (CIMT) measurements are associated with intraoperative hemodynamic changes in adults undergoing liver transplantation. Data come from routine clinical measurements, including CIMT and real-time intraoperative blood pressure and vasopressor records, collected at a single center between January 2023 and January 2026. No additional interventions are introduced; the goal is to see if CIMT can help predict perioperative hemodynamic instability and related complications. Inclusion requires adults 18–65 undergoing elective liver transplantation with CIMT data and consent for data collection; exclusions address carotid stenosis, prior vascular surgeries, significant arrhythmias, and incomplete monitoring data. The study aims to illuminate whether subclinical atherosclerosis assessed preoperatively may relate to intraoperative hemodynamic variability during transplantation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged between 18 and 65 years
* Scheduled for elective liver transplantation surgery
* Completed preoperative carotid intima-media thickness (CIMT) ultrasonographic measurement
* Patients with signed informed consent for data collection

Exclusion Criteria:

* Patients undergoing emergency liver transplantation
* History of previous carotid artery surgery or stenting
* Known severe carotid artery stenosis (\>70%)
* Severe intraoperative hemodynamic instability prior to induction (e.g., active bleeding or shock)
* Incomplete intraoperative advanced hemodynamic monitoring data or vasopressor records

Where it's running

• Dicle University Faculty of Medicine, Department of Anesthesiology and Reanimation
  Diyarbakır, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: ibrahim andan, Asst. Prof.
• Email: ibrahimandan@hotmail.com
• Phone: +905059051167

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.