Evaluating calf circumference for diagnosing sarcopenia in elderly hospitalized patients
Official title: Evaluation of a Diagnostic Method: Calf Circumference Versus X-ray Absorptiometry in the Diagnosis of Sarcopenia in Elderly Hospitalized Participants
Run by Centre Hospitalier Régional d'Orléans · NCT05869487 · Data updated 2026-11-12
This study is testing if measuring calf size can help doctors diagnose sarcopenia in hospitalized patients aged 75 and older, instead of using the more complicated X-ray method.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 75 Years and up |
| Sex | All |
| Enrollment | 298 (estimated) |
| Sponsor | Centre Hospitalier Régional d'Orléans Academic / other |
| Locations | 1 site (Orléans) |
| Status | Recruiting |
| Started | December 11, 2023 |
| Main results expected | April 11, 2027 |
| Study ends | April 11, 2027 |
| Registry record updated | December 30, 2025 |
| Trial ID | NCT05869487 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are hospitalized patients aged 75 years and older who show signs of undernutrition and decreased muscle strength.
✕Probably not a fit
Patients with phenotypic criteria for undernutrition unrelated to sarcopenia or those unable to undergo X-ray absorptiometry will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective single-center study aims to assess the effectiveness of measuring calf circumference as a diagnostic tool for sarcopenia in hospitalized patients aged 75 and older. The study compares this method to the gold standard of X-ray absorptiometry, which is not routinely performed in this population. Participants will be hospitalized individuals with indications of sarcopenia, and measurements will be taken prior to the absorptiometry assessment. The results will be analyzed in a blinded manner to ensure objectivity.
Why it matters
Potential benefit: If successful, this study could provide a simpler and more accessible method for diagnosing sarcopenia in elderly patients, potentially improving their care and outcomes.
How similar studies have gone: While the use of calf circumference as a diagnostic tool has been explored, this specific comparison with X-ray absorptiometry in hospitalized elderly patients is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age greater than or equal to 75 years * Hospitalization in a medical department or in the follow-up care or rehabilitation department of the Hospital Center of Orléans * Presence of an etiological criterion of undernutrition * Presence of a decrease in muscle strength Exclusion Criteria: * Presence of one of two phenotypic criteria for undernutrition other than sarcopenia, which are body mass index less than 22 kilogram per square meter and weight loss (≥ 5 percent over 1 month or ≥ 10 percent over 6 months or ≥10 percent compared with usual weight before the disease). * Refusal to participate in the study * Patient under legal protection * Impossible to perform X-ray absorptiometry (behavioral problems, functional constraints to climb on the DXA machine) * Person not affiliated to a social security system
Where it's running
-
CHU d'Orléans
Orléans, France Recruiting
Study contacts
- Principal investigator: Matthieu COULONGEAT, MD — CHR d'Orléans
- Study coordinator: Elodie Pougoue
- Email: elodie.pougoue-touko@chr-orleans.fr
- Phone: +33238744086
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Sarcopenia in Patients After Cardiac Surgery
This observational study tests how common sarcopenia is after cardiac surgery and whether current care helps improve muscle mass and function.
-
Bone marrow mesenchymal stem cell injection for sarcopenia
This study tests whether CG-BM1, a stem cell injection, can be safely given to adults with sarcopenia to see if it helps improve muscle health.
-
GLP-1 receptor agonist use and muscle health in adults with obesity without diabetes
This study tests whether GLP-1 receptor agonists affect muscle mass and strength in adults with obesity who don’t have diabetes.
-
Sarcopenia and Epidural Steroid Injections in Lumbar Spinal Stenosis
We’re testing how sarcopenia relates to pain, function, and quality of life after a routine interlaminar epidural steroid injection in people with lumbar spinal stenosis.
-
Using Multimodal Ultrasound to Check Muscle Mass in Metabolic Disease Patients
This study tests whether a multimodal ultrasound approach can accurately measure muscle mass in people with metabolic syndrome, obesity, sarcopenia, or type 2 diabetes.
-
Lower-limb rehabilitation robot training with nutrition education for sarcopenia
In adults aged 60 and older with sarcopenia, this study tests whether adding robot-assisted leg training to nutrition education can improve muscle mass and walking ability compared with usual care.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.