Evaluating blood flow and oxygen levels in the brain during laparoscopic gallbladder surgery
Official title: Evaluation of Cerebral Blood Flow and Cerebral Oxygenation With Transcranial Doppler and NIRS in Laparoscopic Cholecystectomy Cases
Run by Uludag University · NCT06036498 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is testing how blood flow and oxygen levels in the brain change during laparoscopic gallbladder surgery to see if certain techniques can help understand any risks involved.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Uludag University Academic / other |
| Locations | 1 site (Bursa, Nilufer) |
| Trial ID | NCT06036498 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 to 65 with an ASA classification of 1-3 scheduled for elective laparoscopic cholecystectomy.
✕Probably not a fit
Patients with ASA classification of 4 and above, those under 18 or over 65, and individuals with a history of cerebrovascular issues will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess changes in cerebral blood flow and oxygenation in patients undergoing laparoscopic cholecystectomy, particularly focusing on the effects of pneumoperitoneum. Researchers will utilize Near Infrared Spectrophotometry (NIRS) and Transcranial Doppler Ultrasonography (TCD) to monitor these changes. The study will compare the outcomes of both assessment methods to determine any significant differences. The findings could provide insights into the neurological risks associated with prolonged laparoscopic surgeries.
Why it matters
Potential benefit: If successful, this study could enhance patient safety by identifying potential neurological complications during laparoscopic surgeries.
How similar studies have gone: While the approach of using NIRS and TCD in this context is relatively novel, similar studies have shown promise in monitoring cerebral perfusion during surgical procedures.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with American Society of Anesthesiology (ASA) 1-3 classification, * Both male and female patients between the ages of 18 to 65, * Patients scheduled for elective laparoscopic cholecystectomy. Exclusion Criteria: * American Society of Anesthesiology (ASA) 4 and above patient groups, * Patients aged under 18 and over 65, * Patients with a history of known previous cerebrovascular accident (CVA), * Patients with follow-up due to Cerebrovascular Ischemic Brain Attack Syndrome (CIBAS), * Patients diagnosed with Carotid Stenosis, * Patients diagnosed with peripheral and central vascular diseases, * Patients with general debilitation and extreme senility, * Cases that require conversion to laparotomy during the intraoperative period.
Where it's running
-
Bursa Uludag University, Faculty of Medicine, Department of Anesthesiology and Reanimation
Bursa, Nilufer, Turkey Recruiting
Study contacts
- Study coordinator: Kadir Bugra Basaran
- Email: kbugrabasaran@gmail.com
- Phone: +905422780016
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.