Treatment of bile duct diseases using a mini-endoscopic system

Diagnosis and Percutaneous Treatment of Biliary Tract Diseases

Not applicable Interventional IRCCS Azienda Ospedaliero-Universitaria di Bologna · NCT06816615

This study is testing a new mini-endoscopic system to see if it can help people with bile duct diseases who can’t have regular endoscopic treatments.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment24 (estimated)
Ages18 Years and up
SexAll
SponsorIRCCS Azienda Ospedaliero-Universitaria di Bologna Academic / other
Locations1 site (Bologna, BO)
Trial IDNCT06816615 on ClinicalTrials.gov

What this trial studies

This study focuses on optimizing the treatment of bile duct diseases in patients who are not candidates for traditional endoscopic procedures. Participants will receive percutaneous cholangioscopic-assisted treatment using the Spyglass system at the University Hospital of Bologna. The study aims to determine if this technique can resolve biliary issues and perform biopsies more efficiently than conventional methods. It includes a 24-month enrollment phase followed by a 36-month follow-up to assess treatment outcomes.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 with a radiological diagnosis of gallstones or bile duct stenosis who are not eligible for endoscopic treatment.

Not a fit: Patients with severe untreatable coagulopathies will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could provide a less invasive and more effective treatment option for patients with bile duct diseases.

How similar studies have performed: While this approach is innovative, similar studies have shown promise in improving outcomes for patients with biliary diseases.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Radiological diagnosis of indeterminate gallstones or stenosis of the bile ducts not eligible for endoscopic treatment and/or previous failed endoscopic treatment
* Good liver function (hemoglobin, hematocrit, GOT, GPT, GGT within normal ranges)
* Age over 18
* Obtaining informed consent

Exclusion Criteria:

* presence of severe untreatable coagulopathies

Where this trial is running

Bologna, BO

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions GallstoneBiliary StrictureBiliary Diseases
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.