Clinical trial Recruiting at 1 site Phase2; Phase3 Interventional Ages 20 to 70

Comparing dexmedetomidine and lignocaine for pain management in laparoscopic gallbladder surgery

Official title: Comparison of Dexmedetomidine & Lignocaine Infusion on Perioperative Hemodynamics, Postoperative Analgesia & Recovery of Postoperative Gastrointestinal Function in Patients for Laparoscopic Cholecystectomy

Run by Sahiwal medical college sahiwal · NCT06740903 · Data updated 2026-11-12

This study is testing whether dexmedetomidine or lignocaine works better for managing pain and recovery in patients having laparoscopic gallbladder surgery.

More Post Operative Pain trials

Quick facts

PhasePhase2; Phase3
Study typeInterventional
Ages20 Years to 70 Years
SexAll
Enrollment140 (estimated)
SponsorSahiwal medical college sahiwal
Government
Locations1 site (Sahiwal, Punjab Province)
StatusRecruiting
StartedAugust 6, 2024
Main results expectedAugust 6, 2025
Study endsSeptember 6, 2025
Registry record updatedDecember 18, 2024
Trial IDNCT06740903 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 20-70 years undergoing elective laparoscopic cholecystectomy with ASA physical status I-II.

Probably not a fit

Patients with emergency surgery needs, significant comorbidities, or contraindications to the trial medications may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the perioperative outcomes of dexmedetomidine versus lignocaine in patients undergoing laparoscopic cholecystectomy. A total of 140 patients will be randomly assigned to receive either dexmedetomidine or lignocaine infusion during surgery to assess their effects on postoperative pain, hemodynamic stability, and gastrointestinal function. The study will be conducted at Sahiwal Medical College over a 12-month period, with careful monitoring of vital signs and pain levels. The goal is to determine which medication provides better analgesia and fewer complications in this surgical setting.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management and reduced complications for patients undergoing laparoscopic cholecystectomy.

How similar studies have gone: Previous studies have shown mixed results regarding the efficacy of dexmedetomidine and lignocaine for postoperative analgesia, making this investigation both relevant and necessary.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients of age 20-70 years
2. Both gender
3. Laparoscopic cholecystectomy under general Anaesthesia
4. ASA I-II.

Exclusion Criteria:

* Emergency surgery
* Patients with history of allergic reaction to trial drugs
* Patients with cardiovascular disease, sickle cell disease, psychiatric disorder, peripheral vascular disease, and neurological diseases (on medical record)
* Anemia
* Patient on TCA or Beta blocker drugs.
* Uncontrolled hypertension (P≥160/100 mmHg)
* Uncontrolled diabetes mellitus
* Obesity BMI \> 35

Where it's running

  • Sahiwal Medical College Sahiwal
    Sahiwal, Punjab Province, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.