ESPB vs SPSIPB for better recovery after VATS

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, double-blind trial compares two ultrasound-guided regional anesthesia techniques—erector spinae plane block (ESPB) and serratus posterior superior intercostal plane block (SPSIPB)—in adults undergoing elective VATS. The primary outcome is the quality of recovery at 24 hours, measured by QoR-15. Secondary outcomes include pain scores, opioid consumption, time to rescue analgesia, nausea and vomiting, satisfaction, hospital stay, block safety, and perioperative hemodynamics. The study plans to enroll 128 patients and is conducted at a Turkish university hospital with a single lead sponsor. Participants are adults 18–70 (up to 85 in eligibility), ASA I–III, without contraindications to regional anesthesia or opioid analgesics, and able to complete QoR-15.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18-85 years.
* ASA physical status I-III.
* Scheduled for elective VATS under general anesthesia.
* Able to understand and complete the QoR-15 questionnaire.
* Written informed consent provided.

Exclusion Criteria:

* Refusal to participate or inability to provide written informed consent.
* Known allergy or contraindication to bupivacaine, paracetamol, dexketoprofen, or tramadol.
* Infection at the planned block injection site.
* Coagulopathy or ongoing anticoagulant therapy precluding regional anesthesia.
* Severe hepatic or renal insufficiency.
* Chronic opioid use or chronic pain requiring regular analgesic treatment.
* Previous thoracic surgery on the operative side.
* Pregnancy or breastfeeding.
* Cognitive impairment, psychiatric illness, or language barrier preventing completion of the QoR-15 questionnaire.
* Body mass index (BMI) \>35 kg/m².
* Conversion from VATS to thoracotomy.
* Failed or incomplete regional block.

Where it's running

• Fatma Acil
  Diyarbakır, Outside of the US, Turkey (Türkiye) Recruiting
• Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
  Diyarbakır, Turkey, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Fatma Acil, M.D. — Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
• Study coordinator: Fatma Acil, M.D.
• Email: acilfatma@gmail.com
• Phone: +905337225225

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.