ESP vs EXORA blocks after laparoscopic nephrectomy
Official title: Prospective Comparison of Postoperative Analgesic Effects of ESP Block and EXORA Block in Nephrectomy Cases
Run by Bakirkoy Dr. Sadi Konuk Research and Training Hospital · NCT07640282 · Data updated 2026-11-12
This observational study compares two pain-control blocks (ESP and EXORA) used after laparoscopic kidney removal to see which provides better pain relief and recovery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 84 (estimated) |
| Sponsor | Bakirkoy Dr. Sadi Konuk Research and Training Hospital Government |
| Locations | 1 site (Istanbul, Istanbul) |
| Status | Recruiting |
| Started | June 5, 2026 |
| Main results expected | August 2029 |
| Study ends | August 2029 |
| Registry record updated | October 21, 2026 |
| Trial ID | NCT07640282 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–80 planned for laparoscopic nephrectomy and for whom the treating clinician has chosen either ESP or EXORA block (ASA I–III).
✕Probably not a fit
Patients who do not experience pain relief from the chosen block or who have characteristics limiting block effectiveness may see little to no benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Researchers observe adults undergoing laparoscopic nephrectomy who receive either an Erector Spinae Plane (ESP) block or an External Oblique Rectus Abdominis (EXORA) block as part of routine care. The study records block type, demographic information, and recovery using a QoR-15 questionnaire before surgery and 24 hours after. All participants receive standard postoperative analgesia, and the investigators do not intervene in clinical decisions or care. The aim is to see if one block offers superior pain control or improves recovery quality compared with the other. No experimental manipulation is performed; data come from routine clinical practice at a single center in Istanbul.
Why it matters
Potential benefit: If one block shows clearer advantages, future practice guidelines could favor that technique to improve recovery.
How similar studies have gone: Previous reports on regional blocks for abdominal surgery show variable results; this study provides observational data on two related approaches within routine care.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age between 18 and 80 years * Patients scheduled for laparoscopic nephrectomy * Patients for whom Erector Spinae Plane (ESP) block or External Oblique Rectus Abdominis (EXORA) block has been selected by the treating clinician * ASA physical status I-III Exclusion Criteria: * No regional block performed in routine clinical practice * Body mass index (BMI) greater than 35 kg/m² * History of opioid dependence * Alcohol or other substance dependence * Psychiatric disease, mental retardation, dementia, or any condition impairing pain perception or pain assessment
Where it's running
-
Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Istanbul, Istanbul, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Şeyma Nur Güner Zengin, MD
- Email: snurguner@gmail.com
- Phone: +90 212 414 71 71
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.