Energy-based therapies vs standard surgery for Grade III hemorrhoids

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter, pragmatic trial compares Laser Hemorrhoidoplasty, Hemorrhoid Energy Therapy, and conventional Ferguson hemorrhoidectomy in patients with Goligher Grade III internal hemorrhoids. Participants choose their preferred treatment after standardized counseling, and analyses use propensity score overlap weighting to reduce bias. Primary outcomes include postoperative pain over the first two weeks and time to functional recovery, with secondary outcomes on 12-month recurrence, symptom severity, quality of life, and complications. An independent blinded committee will adjudicate recurrences. The study aims to identify whether less invasive energy-based options provide better short-term comfort and comparable long-term results to open surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosed with Goligher Grade III internal hemorrhoids.
* Symptomatic with HDSS score \>= 5.
* Age 18-75 years.
* Fit for general anesthesia or sedation.
* Able to provide informed consent.
* Agree to pre-operative photo documentation.

Exclusion Criteria:

* Other anorectal diseases (fistula, abscess, IBD, malignancy).
* Prior anorectal surgery within 6 months.
* Pregnancy or lactation.
* Contraindications to anesthesia.

Where it's running

• Chang Gung Memorial Hospital, Linkou Branch
  Taoyuan, Taiwan Recruiting

Study contacts

• Study coordinator: I-Li Lai, MD
• Email: ryane92a5@gmail.com
• Phone: +886911978067

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Hemorrhoidal artery embolization to improve internal hemorrhoid symptoms

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• Investigating the link between cough and hemorrhoids

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  Recruiting Muğla Sıtkı Koçman University · Muğla, Menteşe · NCT06878209

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.