Hemorrhoid Artery Embolization (HAE) for Bleeding Internal Hemorrhoids: A Real-World Registry

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective registry records long-term outcomes of patients undergoing hemorrhoid artery embolization (HAE) for symptomatic internal hemorrhoidal bleeding. Participants are adults 18 and older who have not responded to medical therapy and are treated as part of routine care. Follow-up occurs at 1, 3, 6, 12, 18, 24, and 36 months to track bleeding, symptoms, and quality of life, with safety data collected per interventional radiology guidelines. There is no randomized control group; analyses will identify predictors of success and help refine patient selection and best practices for HAE. The study is observational and aims to understand real-world effectiveness and safety of HAE in this population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults (≥18 years) with symptomatic bleeding internal hemorrhoids refractory to medical therapy, referred for HAE.

Exclusion Criteria:

* Pregnancy, coagulopathy, severe comorbidities, or inability to consent.

Where it's running

• Joint and Vascular Institute
  Libertyville, Illinois, United States Recruiting

Study contacts

• Study coordinator: Layth Alkhani, BS
• Email: lalkhani@jointvascular.com
• Phone: 847-584-3959

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Topical nifedipine 0.3% plus lidocaine 1.5% for uncomplicated hemorrhoids

  This will try topical nifedipine 0.3% plus lidocaine 1.5% applied rectally and perianally twice daily to reduce symptoms in adults with uncomplicated acute hemorrhoids.

  Recruiting Cardarelli Hospital · Naples · NCT07295886

• Comparing latex and non-latex bands for treating hemorrhoids

  This study is testing whether non-latex bands work as well as latex bands for treating hemorrhoids in adults and looking at any side effects they might cause.

  Recruiting Huntington Memorial Hospital · Pasadena, California · NCT06625138

• SHAPE vs. Milligan-Mordon hemorrhoidectomy for advanced hemorrhoids

  This trial tests whether Skin-Sparing Hemorrhoidectomy and PExy (SHAPE) works as well as the conventional Milligan-Morgan procedure for adults with severe hemorrhoids.

  Recruiting Cairo University · Cairo, Al-Manial, Cairo, Egypt · NCT07598630

• Hemorrhoidal artery embolization versus rubber band ligation for internal hemorrhoid bleeding

  This trial will test whether hemorrhoidal artery embolization or rubber band ligation better stops bleeding and improves symptoms in adults with internal hemorrhoids.

  Recruiting University of California, Los Angeles · Los Angeles, California · NCT07559630

• Laser hemorrhoidoplasty outcomes in internal hemorrhoids

  This study tests how patients with symptomatic internal hemorrhoids fare after laser hemorrhoidoplasty, focusing on pain, complications, and satisfaction after the procedure.

  Recruiting Sanliurfa Education and Research Hospital · Sanliurfa, Şanlıurfa · NCT07520734

• Energy-based therapies vs standard surgery for Grade III hemorrhoids

  This trial tests three surgical options—two energy-based methods and conventional hemorrhoidectomy—to see which relieves pain and helps people recover fastest.

  Recruiting Chang Gung Memorial Hospital · Taoyuan · NCT07333040

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.