Early PONV: Registry Insights from Swedish Perioperative Data
Official title: Risk of Early Postoperative Nausea and Vomiting (PONV) - a Study With Data From the Swedish Perioperative Register (SPOR).
Run by Västernorrland County Council, Sweden · NCT04433676 · Data updated 2026-11-12
This study uses Swedish registry data to see how often nausea and vomiting happen soon after surgery and what factors are linked to it in adults after different procedures.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1500000 (estimated) |
| Sponsor | Västernorrland County Council, Sweden Government |
| Locations | 1 site (Sundsvall, X) |
| Status | Recruiting |
| Started | January 1, 2016 |
| Main results expected | December 31, 2029 |
| Study ends | December 31, 2029 |
| Registry record updated | August 19, 2026 |
| Trial ID | NCT04433676 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18 years or older) who underwent surgery under general or regional anesthesia and have PONV data available in SPOR.
✕Probably not a fit
Patients without complete PONV data in SPOR or those not represented in the registry may not benefit from the insights.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study analyzes data from the Swedish Perioperative Registry (SPOR) from 2016 to 2022 to estimate the risk of early postoperative nausea and vomiting (PONV) at the recovery unit. It compares cohorts defined by procedure type or time period and identifies factors associated with early PONV. Data are extracted yearly from SPOR, with hospitals able to contribute additional PONV data if they record it, facilitating national-level risk description. No experimental intervention is performed; the aim is descriptive risk characterization and identification of potential predictors. The project leverages a large, real-world surgical dataset to inform future prevention efforts.
Why it matters
Potential benefit: Understanding the risk and factors for early PONV could inform improved prevention and management strategies in the recovery unit.
How similar studies have gone: Previous registries and observational analyses have successfully characterized PONV risk patterns in surgical populations using large national datasets.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Procedure under general or regional anaesthesia * Age \>=18 years at the day of the procedure. Exclusion Criteria: * No entry of the PONV-variable in the SPOR-registry
Where it's running
-
Västernorrland County Council / Sundsvall Hospital
Sundsvall, X, Sweden Recruiting
Study contacts
- Principal investigator: Jakob Wallden, MD PhD — Region Västernorrland (Västernorrland County Council)
- Study coordinator: Jakob Wallden, MD PhD
- Email: jakob.wallden@umu.se
- Phone: 0046703644392
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.