Clinical trial Recruiting at 1 site Observational Ages 18 to 75

Intraoperative Warmth and Moisture for VATS: Do Humidified Gases Help After Thoracic Surgery?

Official title: Clinical Effects of Active Versus Passive Intraoperative Respiratory Gas Humidification During Video-Assisted Thoracoscopic Surgery: A Prospective Single-Center Observational Cohort Study

Run by Marmara University · NCT07729319 · Data updated 2026-11-12

This observational study looks at whether using heated, humidified gases during VATS with one-lung ventilation helps reduce lung-related postoperative problems.

More Postoperative Complications trials

Quick facts

Study typeObservational
Ages18 Years to 75 Years
SexAll
Enrollment200 (estimated)
SponsorMarmara University
Academic / other
Locations1 site (Istanbul, Istanbul)
StatusRecruiting
StartedJuly 25, 2026
Main results expectedApril 2027
Study endsApril 2027
Registry record updatedJuly 27, 2026
Trial IDNCT07729319 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18–75 undergoing elective VATS lung resection with planned one-lung ventilation.

Probably not a fit

Patients not at risk for PPCs or those not receiving one-lung ventilation may not experience noticeable benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, single-center cohort follows adults 18–75 undergoing elective VATS lung resection with planned one-lung ventilation. It compares two intraoperative gas conditioning methods: active heated humidification versus passive heat and moisture exchangers. The goal is to see if humidified gases influence postoperative pulmonary complications and airway clearance. Data are collected perioperatively to observe associations rather than causal effects. The study is conducted at Marmara University in Istanbul.

Why it matters

Potential benefit: If successful, using heated humidification could lower postoperative pulmonary complications and improve recovery after thoracic surgery.

How similar studies have gone: Evidence in ICU or prolonged ventilation supports humidification benefits, but data in thoracic surgery with one-lung ventilation are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients aged 18 to 75 years
* Elective video-assisted thoracoscopic surgery (VATS)
* Lung resection requiring general anesthesia
* Planned one-lung ventilation
* Written informed consent

Exclusion Criteria:

* Emergency surgery
* Pregnancy
* Preoperative mechanical ventilation
* Previous enrollment
* Refusal to participate

Where it's running

  • Marmara University
    Istanbul, Istanbul, Turkey (Türkiye)
    Recruiting

Study contacts

  • Principal investigator: Seniyye Ülgen Zengin, Associate Professor — Marmara University
  • Study coordinator: Nezaket Nur Arslan Kömür, MD
  • Email: nnurarslan@gmail.com
  • Phone: +905392911654

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.