Early Cognitive Interventions in Digital Format for Cancer Survivors: Home-Based Training for CRCI

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial compares two home-based cognitive training platforms—BrainHQ (computerized exercises) and Enhance VR (virtual reality) against a control group. Adults with stage I–III cancer and subjective cognitive concerns within 1–6 months after chemotherapy are randomized to one of the two interventions or control. Interventions last 10 weeks with pre- and post-assessments to evaluate changes in cognitive function and user acceptability. The study emphasizes usability, adherence, and potential transfer of cognitive gains to daily activities.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients over 18 years of age diagnosed with cancer (stage I-III)
* Subjective complaints of cognitive functioning related to the diagnosis of cancer and/or cancer treatments
* Between 1-6 months after completion of chemotherapy treatment
* To have Wi-Fi and a computer/tablet
* To sign the informed consent form

Exclusion Criteria:

* Previous history of cancer diagnosis
* Anticipated change in cancer treatment/general medical treatment during the intervention period
* Previous diagnosis of cognitive impairment
* Diagnosis of other neurological or psychiatric diseases
* Diagnosis of severe untreated depression
* History of episodes of vertigo, epilepsy or seizures
* Currently undergoing or having undergone any other type of intervention aimed at improving cognitive functioning (e.g., CRCI workshops)
* Severe visual or hearing difficulties that may affect the performance of the intervention exercises
* Inability to speak, understand, read, and write Spanish correctly
* Failure to sign the informed consent form

Where it's running

• Hospital Universitario Basurto
  Bilbao, Bizkaia, Spain Recruiting
• Hospital Universitario Galdakao-Usansolo
  Galdakao, Bizkaia, Spain Recruiting
• Hospital Universitario Donostia
  San Sebastián, Gipuzkoa, Spain Recruiting

Study contacts

• Study coordinator: Dr. Ander Urruticoechea Ribate
• Email: ander.urruticoechearibate@osakidetza.eus
• Phone: +34943328000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.