Does adding a TAP block with low-dose ropivacaine help after cesarean birth?
Official title: Comparative Analysis of the Impact of Transversus Abdominis Plane Block on Post-Cesarean Pain Management Using Low Concentration Ropivacaine 0,2%
Run by Tîrgu Mureș Emergency Clinical County Hospital, Romania · NCT07604376 · Data updated 2026-11-12
This study tests whether adding a TAP block to standard pain relief after cesarean delivery reduces pain and opioid use in the first 24 hours for women.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 70 (estimated) |
| Sponsor | Tîrgu Mureș Emergency Clinical County Hospital, Romania Academic / other |
| Locations | 1 site (Târgu Mureş, Mureș County) |
| Status | Recruiting |
| Started | March 1, 2024 |
| Main results expected | July 31, 2026 |
| Study ends | December 31, 2027 |
| Registry record updated | May 22, 2026 |
| Trial ID | NCT07604376 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women undergoing cesarean section with spinal anesthesia who meet the local eligibility criteria.
✕Probably not a fit
Patients who do not experience a reduced pain score or lower opioid use may not benefit from adding the TAP block.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional trial compares a Transversus Abdominis Plane (TAP) block using ropivacaine 0.2% at 0.4 ml/kg per side to the hospital's traditional analgesia after cesarean section. Participants receive spinal anesthesia and are randomized to TAP plus standard care or standard care alone, with pain scores and opioid use tracked during the first 24 hours and recovery quality assessed. The TAP group uses ultrasound guidance for block placement, followed by a defined postoperative analgesia regimen, while the control group follows the hospital’s usual analgesia protocol. The study measures postoperative pain, opioid consumption, and 24-hour recovery outcomes to determine the added value of the TAP block. Eligible patients are those undergoing cesarean delivery with spinal anesthesia, excluding those with certain anesthesia or obstetric emergencies.
Why it matters
Potential benefit: If successful, patients may experience less pain and lower opioid needs after cesarean delivery.
How similar studies have gone: Previous research on TAP blocks for cesarean pain has shown potential benefits in pain control and opioid reduction, though results vary by protocol.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: pregnant patient anaesthesia type for c-section: spinal Exclusion Criteria: general anaesthesia for c-section combined spinal/epidural anaethesia for c-section hipertensive emergencies in obstetrics haemorrhage emergencies in obstetrics
Where it's running
-
County Emergency Clinical Hospital of Targu Mureș
Târgu Mureş, Mureș County, Romania Recruiting
Study contacts
- Principal investigator: Matild Keresztes — Department of Anesthesiology and Intensive Care, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mureș
- Study coordinator: Matild Keresztes, Medical doctor
- Email: keresztesmatild@gmail.com
- Phone: +40741784066
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.