DLBCL in the MEA region: how patients are treated and access to new therapies

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational study conducted at multiple centers in the MEA region to describe clinical characteristics, treatment patterns, and access to novel therapies for adults with diffuse large B-cell lymphoma. The trial documents real-world data, including diagnostic workups, treatment decisions, and subsequent outcomes, without assigning specific treatments. Cohorts include patients starting treatment and those who have failed prior lines of therapy, with consent obtained from participants. No interventional procedures are mandated beyond clinical care and data collection. The study is sponsored by AstraZeneca and involves sites in Al Mansurah, Alexandria, and Cairo.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Male or female patients aged 18 years or older at diagnosis.
2. Patients who have confirmed diagnosis of diffuse large B-cell lymphoma (DLBCL) according to the investigator's decision and/or histopathological diagnosis.
3. For Cohort 1: DLBCL patients who are eligible to start treatment\* according to the investigator's decision.
4. For Cohort 2: patients who are diagnosed with DLBCL and have failed at least one prior line of therapy.
5. Patients willing to sign the written informed consent form (ICF) indicating that they understand the purpose of the study and procedures required for participation.

Exclusion Criteria:

1. Patients who are not eligible for treatment for any reason, according to the investigator's judgment and decision
2. Patients with concurrent active malignancies other than DLBCL.
3. Patients who are actively participating in any other clinical trial.

Where it's running

• Research Site
  Amman, Jordan Recruiting
• Research Site
  Muscat, Oman Recruiting
• Research Site
  Doha, Qatar Recruiting
• Research Site
  Dammam, Saudi Arabia Recruiting
• Research Site
  Jeddah, Saudi Arabia Recruiting
• Research Site
  Riyadh, Saudi Arabia Recruiting

Study contacts

• Study coordinator: AstraZeneca Clinical Study Information Center
• Email: information.center@astrazeneca.com
• Phone: 1-877-240-9479

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Personalized goal-based rehabilitation during pediatric stem cell transplant

  This will try a personalized Goal Attainment Scale to help children and teens (6 months–17 years) keep or improve physical abilities during hematopoietic stem cell transplantation.

  Recruiting Azienda Ospedaliera Ospedale Infantile Regina Margherita Sant'Anna · Torino, TO · NCT07372690

• Donor-recipient sex matching for red blood cell transfusions in adult ICU patients

  We will test whether giving adult ICU patients red blood cell transfusions from donors of the same sex improves survival compared with transfusions from donors of the opposite sex.

  Recruiting Phase 4 McMaster University · Hamilton, Ontario and 7 other locations · NCT06840756

• Comparing thigh ultrasound muscle size with whole-body muscle measurements after cancer

  This study tests whether a quick ultrasound of the thigh can estimate whole-body muscle mass in adults who have completed cancer treatment.

  Recruiting Hospices Civils de Lyon · Pierre-Bénite · NCT06007794

• Geriatric assessment before CAR‑T or bispecific antibody therapy to predict side effects and outcomes in older adults

  This study will test whether a brief geriatric assessment done before CAR‑T or bispecific antibody treatment can help predict side effects and outcomes for people aged 65 and older with aggressive lymphoma or multiple myeloma.

  Recruiting at 2 sites University of Zurich · Bern and 1 other locations · NCT07309497

• Online physical activity program for children and adolescents with cancer

  This study tests an online exercise program for kids and teens with cancer to see if it helps them feel better during their treatment.

  Recruiting at 2 sites University of Calgary · Calgary, Alberta and 1 other locations · NCT04956133

• Investigating how anti-infectives work in critically ill children

  This study is trying to see how different anti-infective medications work in critically ill children to help figure out the best doses for them.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT02539407

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.