Comparing thigh ultrasound muscle size with whole-body muscle measurements after cancer
Official title: Correlation Between Ultrasound-assessed Quadriceps Muscle Mass and Baseline Whole-body Densitometry Muscle Index in the Post-cancer Population (JUMP Research II)
Run by Hospices Civils de Lyon · NCT06007794 · Data updated 2026-11-12
This study tests whether a quick ultrasound of the thigh can estimate whole-body muscle mass in adults who have completed cancer treatment.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 74 Years |
| Sex | All |
| Enrollment | 55 (estimated) |
| Sponsor | Hospices Civils de Lyon Academic / other |
| Locations | 1 site (Pierre-Bénite) |
| Status | Recruiting |
| Started | February 10, 2025 |
| Main results expected | February 10, 2029 |
| Study ends | May 10, 2029 |
| Registry record updated | September 16, 2025 |
| Trial ID | NCT06007794 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18–74 who have completed treatment for breast, lung, melanoma, testicular, bladder, kidney, ovarian, colon, pancreatic cancers or hematologic malignancies and who attend the post-cancer assessment day are ideal candidates.
✕Probably not a fit
Patients with active cancer, pregnancy or breastfeeding, major cognitive impairment, bilateral lower-limb amputation, or unable to understand French are unlikely to benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults aged 18–74 who have completed treatment for select cancers attend a post-cancer assessment day that includes ultrasound of the quadriceps and whole-body densitometry to measure muscle mass. The protocol compares ultrasound-derived quadriceps measurements with a baseline whole-body muscle index from densitometry to determine how well the local ultrasound reflects total muscle mass. Participants with active cancer, pregnancy, major cognitive impairment, bilateral lower-limb amputation, or insufficient French language comprehension are excluded. After the evaluation, patients are referred to appropriate rehabilitation or adapted physical-activity programs as needed.
Why it matters
Potential benefit: If successful, clinicians could use a fast, low-cost thigh ultrasound to screen for muscle loss and refer survivors to rehabilitation sooner.
How similar studies have gone: Previous work in older adults and some cancer groups has shown good correlation between muscle ultrasound and whole-body densitometry, but evidence across diverse post-cancer populations is still limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age : 18 to 74 years * localization of the primitive: breast, lung, melanoma, testicle, bladder, kidney, ovary, colon and pancreas, hemopathy * patient who benefited from the post-cancer assessment day Exclusion Criteria: * Active cancer (relapse or new cancer) * Pregnant or breastfeeding women * Major cognitive impairment making comprehension and exercise difficult * Amputation of both lower limbs (for ultrasound) * Difficulty understanding oral and written French * Adults under legal protection (guardianship, curatorship or safeguard of justice)
Where it's running
-
Hôpital Lyon Sud, rhumatologie
Pierre-Bénite, France Recruiting
Study contacts
- Study coordinator: Cyrille CONFAVREUX, Md,PhD
- Email: Cyrille.confavreux@chu-lyon.fr
- Phone: +33 4 78 86 12 31
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.