Differences in Outcomes After Allograft vs Autograft in Revision ACL Repair

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study examines outcomes after revision ACL reconstruction to compare allografts and autografts. It focuses on patients 18–50 undergoing revision surgery and tracks outcomes for at least two years. Graft choice and surgical details may influence stability and rerupture risk, which can be higher in revisions. The study builds on known rerupture rates and aims to clarify how graft type affects overall outcomes in a real-world setting.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18-50 years at the time of surgery
* Male and female patients
* Patients undergoing revision anterior cruciate ligament (ACL) reconstruction with possible associated procedures, with at least 2 years of follow-up
* Written informed consent to participate in the study

Exclusion criteria:

* Patients lost to follow-up
* Refusal to provide informed consent
* Advanced knee osteoarthritis (Outerbridge grade III-IV) at the time of surgery
* Severe obesity (BMI \> 35)
* Lower limb conditions preventing full weight-bearing standing during evaluation
* Active infection, hematologic disease, or rheumatologic disease at the time of assessment

Where it's running

• IRCCS Rizzoli Orthopedic Institute
  Bologna, Bologna, Italy Recruiting

Study contacts

• Study coordinator: stefano zaffagnini
• Email: stefano.zaffagnini@unibo.it
• Phone: 0516366075

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Functional brain signal changes after ACL reconstruction with targeted neuromotor training

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  Recruiting Istituto Ortopedico Rizzoli · Bologna, Bologna · NCT07097077

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.