Detecting cancer risk in pancreatic cysts using new tests

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of new biomarkers found in blood, stool, pancreatic cyst fluid, and pancreatic juice for diagnosing malignant or pre-malignant changes in pancreatic cysts. Participants with Fukuoka Worrisome or Fukuoka High Risk pancreatic cysts will be enrolled and assigned to either Immediate Surgery or Clinical Follow-up groups based on their clinical management. Specimens will be collected from participants to assess the presence of these biomarkers and their correlation with cyst malignancy. The study is designed to improve diagnostic accuracy and patient outcomes in managing pancreatic cysts.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with pancreatic cystic lesions meeting Fukuoka worrisome or Fukuoka high-risk criteris
* Patients with suspected cystic neoplasm of the pancreas
* Able to provide written informed consent

Exclusion Criteria:

* Pregnant and/or nursing
* Incarceration
* Imaging showing possible pancreatic cancer
* Prior history of pancreatic cancer or pancreatic surgery
* History of receiving systemic chemotherapy or abdominal radiation within the last 5 years
* Previous therapy for a pancreatic cystic lesion
* History of pancreatic necrosis
* Diagnosis of cancer (other than non-melanoma skin cancer) within the last 5 years

Where it's running

• Mayo Clinic
  Rochester, Minnesota, United States Recruiting

Study contacts

• Principal investigator: Shounak Majumder, MD — Mayo Clinic
• Study coordinator: IN-CYST Team
• Email: rstincyststudy@mayo.edu
• Phone: 1-833-250-5364

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Research on early detection of pancreatic cancer

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.