Deep Subgluteal Block vs PENG + LFCN Block for Hip Arthroplasty Pain
Official title: Comparison of Deep Subgluteal Block and Pericapsular Nerve Group Block Combined With Lateral Femoral Cutaneous Nerve Block for Postoperative Analgesia After Hip Arthroplasty: A Randomized Prospective Study
Run by Medipol University · NCT07770932 · Data updated 2026-11-12
This randomized study compares two ultrasound-guided nerve blocks to see which provides better pain control after hip replacement.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Medipol University Academic / other |
| Locations | 1 site (Istanbul, Bagcilar) |
| Status | Recruiting |
| Started | August 1, 2026 |
| Main results expected | December 30, 2026 |
| Study ends | January 30, 2027 |
| Registry record updated | August 18, 2026 |
| Trial ID | NCT07770932 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–80 scheduled for elective hip arthroplasty under general anesthesia, ASA I–III, able to consent and use a PCA device.
✕Probably not a fit
Patients unlikely to benefit include those with contraindications to regional anesthesia or amide local anesthetic sensitivity, and those not meeting eligibility criteria.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
In this randomized, prospective, double-blind trial, 60 adults undergoing hip arthroplasty under general anesthesia are assigned to receive either a Deep Subgluteal Block or a Pericapsular Nerve Group block with a LFCN block, with all local anesthetic doses and volumes standardized. The primary outcome is total fentanyl use in the first 24 hours after surgery; secondary outcomes include pain scores at rest and with movement, quadriceps motor block, and opioid-related side effects. Procedures are performed postoperatively by an experienced anesthesiologist under ultrasound guidance to maintain blinding.
Why it matters
Potential benefit: If successful, the preferred block could reduce opioid needs and improve early postoperative pain control after hip arthroplasty.
How similar studies have gone: Previous regional anesthesia studies suggest block techniques can affect analgesia, but direct head-to-head comparison of DSGB versus PENG+LFCN for hip arthroplasty analgesia is not well established.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients scheduled for elective total or partial hip arthroplasty under general anesthesia * American Society of Anesthesiologists (ASA) physical status I-III * Aged between 18 and 80 years * Able to understand the study procedures, give voluntary written informed consent, and operate a patient-controlled analgesia (PCA) device Exclusion Criteria: * Patient refusal or inability to provide informed consent * Pre-existing peripheral neuropathy, cognitive impairment, or psychiatric disorders * History of significant severe renal or hepatic failure * Allergy or hypersensitivity to amide-type local anesthetics or opioids * Infection, severe anatomic distortion, or previous surgery at the proposed block injection sites * History of substance abuse or chronic opioid use (defined as daily opioid use for \> 3 months prior to surgery)
Where it's running
-
Medipol Mega University Hospital
Istanbul, Bagcilar, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Yunus O Atalay, MD, Prof., DESAIC
- Email: yoatalay@medipol.edu.tr
- Phone: +90 212 453 4800
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.