Daily fisetin supplement to support healthy aging

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a randomized, triple-blind, placebo-controlled two-arm trial enrolling about 120 relatively healthy middle-aged and older adults. Participants will be randomly assigned to receive either a 100 mg fisetin capsule or a matching placebo once daily for seven weeks. The study will monitor markers of inflammation, overall health measures, and safety outcomes during and after the intervention. Enrollment is limited to participants who can read Danish and attend visits at the study site in Hvidovre, Denmark.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Middle-aged or older adult (≥50 years),
* Able to cooperate cognitively,
* Able to read and understand Danish,

Exclusion Criteria:

* Inability or unwillingness to take oral supplements,
* Chronic or recent (within 30 days) use of other anti-aging supplements,
* Chronic or recent (within 30 days) treatment with medications having anti-aging effects (e.g., metformin, rapamycin, semaglutide),
* Chronic or recent (within 30 days) treatment with anti-inflammatory medications,
* Chronic or recent (within 30 days) treatment with the medications that can interact negatively with fisetin,
* Recent (within 14 days) vaccination,
* Treatment with another investigational drug or other intervention within 1 year,
* Active cancer or current cancer treatment,
* Unstable or uncontrolled major disorders, e.g., cardiovascular, renal, endocrine, immunological, hepatic disorder, or cancer, requiring regular monitoring at the hospital
* Planned medical and surgical procedures during the study period,
* Known hypersensitivity or allergy to fisetin or excipients in the placebo capsules,
* Presence of any condition that the investigator believes would put the participant at risk or would preclude the participant from successfully completing all aspects of the study

Where it's running

• Department of Clinical Research, Copenhagen University Hospital Amager & Hvidovre
  Hvidovre, Denmark Recruiting

Study contacts

• Study coordinator: Juliette Tavenier
• Email: juliette.tavenier@regionh.dk
• Phone: +45 38620958

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Do Quercefit® or Ubiqsome™ help with aging and metabolic health in adults 50–75?

  This study tests whether Quercefit® or Ubiqsome™ can improve aging markers, blood sugar, and heart health in sedentary adults aged 50–75 compared with a placebo.

  Recruiting Applied Science & Performance Institute · Tampa, Florida · NCT07760506

• NVTIA Ergothioneine for Healthy Aging and Skin Health

  This study tests whether taking NVTIA Ergothioneine daily for 12 weeks helps healthy adults age more gracefully and keeps skin looking and feeling better compared with a placebo.

  Recruiting European Life Science Research Association · Dhaka · NCT07750002

• Miricell supplementation and markers of healthy aging

  This trial tests whether taking Miricell once daily for 12 weeks improves cellular health and brain/metabolic indicators in adults aged 40–70 compared with a placebo.

  Recruiting Nutraland USA, Inc. · Canfield, Ohio · NCT07675200

• Does daily lean beef support brain health in older adults

  In healthy adults aged 65 and up, this study tests whether eating lean beef every day for two weeks can influence brain health markers compared with a non-beef, protein-matched option.

  Recruiting South Dakota State University · Brookings, South Dakota · NCT07623785

• Adaptive computerized training to boost thinking in healthy seniors and those with mild cognitive impairment

  This study tests whether a computer-based training program can improve executive thinking in older adults, including those with mild cognitive impairment, and see if it also helps memory and well-being.

  Recruiting at 2 sites Universidad Antonio de Nebrija · Madrid, Madrid and 1 other locations · NCT07598409

• SHARP: Personalized Health and Behavior Plan to Lower Biological Age in Older Adults

  A 12-month randomized trial tests whether a personalized health and behavior program can lower biological age and improve function in healthy adults over 50.

  Recruiting Sheba Medical Center · Ramat Gan, Tel Aviv · NCT07596576

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.