Creating a database to study variations in motor neuron diseases
Official title: Creazione di un Database Clinico Per lo Studio Della variabilità Fenotipica Nella Malattia Del Motoneurone
Run by Istituto Auxologico Italiano · NCT06318585 · Data updated 2026-11-12
This study is trying to learn more about the different types of motor neuron diseases in patients to better understand the condition and improve how we predict its course.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Istituto Auxologico Italiano Academic / other |
| Locations | 1 site (Milan, MI) |
| Status | Recruiting |
| Started | April 3, 2023 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | May 7, 2025 |
| Trial ID | NCT06318585 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals diagnosed with amyotrophic lateral sclerosis or other motor neuron diseases.
✕Probably not a fit
Patients who refuse to participate in the study will not benefit from its findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to characterize the clinical presentation of motor neuron diseases (MND) in patients at the Neurology Department of the Istituto Auxologico Italiano. It will assess specific clinical phenotypes associated with MND and explore how these phenotypes can enhance understanding of the disease mechanisms and improve prognostic accuracy. Participants will undergo clinical evaluations, neurophysiological and neuroradiological assessments, neuropsychological evaluations, and may provide biological materials for genetic screening and biomarker assessment.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of motor neuron diseases, potentially enhancing patient outcomes.
How similar studies have gone: While similar studies have been conducted, this approach focuses specifically on the phenotypic variability in motor neuron diseases, making it a novel contribution to the field.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * diagnosis of ALS or other motor neuron disease Exclusion Criteria: * refusal to participate to the study
Where it's running
-
Ospedale San Luca
Milan, Mi, Italy Recruiting
Study contacts
- Study coordinator: Nicola Ticozzi, MD, PhD
- Email: n.ticozzi@auxologico.it
- Phone: +390261911
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.