Clinical trial Recruiting at 1 site Observational Ages 18 and up

Creating a database to study variations in motor neuron diseases

Official title: Creazione di un Database Clinico Per lo Studio Della variabilità Fenotipica Nella Malattia Del Motoneurone

Run by Istituto Auxologico Italiano · NCT06318585 · Data updated 2026-11-12

This study is trying to learn more about the different types of motor neuron diseases in patients to better understand the condition and improve how we predict its course.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment200 (estimated)
SponsorIstituto Auxologico Italiano
Academic / other
Locations1 site (Milan, MI)
StatusRecruiting
StartedApril 3, 2023
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedMay 7, 2025
Trial IDNCT06318585 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals diagnosed with amyotrophic lateral sclerosis or other motor neuron diseases.

Probably not a fit

Patients who refuse to participate in the study will not benefit from its findings.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to characterize the clinical presentation of motor neuron diseases (MND) in patients at the Neurology Department of the Istituto Auxologico Italiano. It will assess specific clinical phenotypes associated with MND and explore how these phenotypes can enhance understanding of the disease mechanisms and improve prognostic accuracy. Participants will undergo clinical evaluations, neurophysiological and neuroradiological assessments, neuropsychological evaluations, and may provide biological materials for genetic screening and biomarker assessment.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding and management of motor neuron diseases, potentially enhancing patient outcomes.

How similar studies have gone: While similar studies have been conducted, this approach focuses specifically on the phenotypic variability in motor neuron diseases, making it a novel contribution to the field.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* diagnosis of ALS or other motor neuron disease

Exclusion Criteria:

* refusal to participate to the study

Where it's running

  • Ospedale San Luca
    Milan, Mi, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.