Creating a database to study variations in motor neuron diseases
Creazione di un Database Clinico Per lo Studio Della variabilità Fenotipica Nella Malattia Del Motoneurone
This study is trying to learn more about the different types of motor neuron diseases in patients to better understand the condition and improve how we predict its course.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Istituto Auxologico Italiano Academic / other |
| Locations | 1 site (Milan, MI) |
| Trial ID | NCT06318585 on ClinicalTrials.gov |
What this trial studies
This observational study aims to characterize the clinical presentation of motor neuron diseases (MND) in patients at the Neurology Department of the Istituto Auxologico Italiano. It will assess specific clinical phenotypes associated with MND and explore how these phenotypes can enhance understanding of the disease mechanisms and improve prognostic accuracy. Participants will undergo clinical evaluations, neurophysiological and neuroradiological assessments, neuropsychological evaluations, and may provide biological materials for genetic screening and biomarker assessment.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with amyotrophic lateral sclerosis or other motor neuron diseases.
Not a fit: Patients who refuse to participate in the study will not benefit from its findings.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of motor neuron diseases, potentially enhancing patient outcomes.
How similar studies have performed: While similar studies have been conducted, this approach focuses specifically on the phenotypic variability in motor neuron diseases, making it a novel contribution to the field.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * diagnosis of ALS or other motor neuron disease Exclusion Criteria: * refusal to participate to the study
Where this trial is running
Milan, MI
- Ospedale San Luca — Milan, Mi, Italy (Recruiting)
Study contacts
- Study coordinator: Nicola Ticozzi, MD, PhD
- Email: n.ticozzi@auxologico.it
- Phone: +390261911
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.