Understanding the variability in ALS through biomarkers

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the clinical variability among patients with Amyotrophic Lateral Sclerosis (ALS) by utilizing multidimensional biomarkers. It seeks to identify which biomarkers correlate with genetic and phenotypic characteristics of ALS and to categorize patients into more homogeneous subgroups. Participants will undergo a series of evaluations, including neurological, neurophysiological, and neuropsychological assessments, along with whole exome sequencing and biomarker measurements in cerebrospinal fluid and plasma.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* diagnosis of ALS or other motor neuron disease
* residence near the study centers

Exclusion Criteria:

* refusal to participate to the study
* unable/unwilling to perform follow-up visits

Where it's running

• Ospedale San Raffaele
  Milan, Mi, Italy Recruiting
• Ospedale San Luca
  Milan, Mi, Italy Recruiting
• AOU Città della Salute e della Scienza
  Torino, To, Italy Recruiting

Study contacts

• Study coordinator: Nicola Ticozzi, MD, PhD
• Email: n.ticozzi@auxologico.it
• Phone: +390261911

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.