Comparison of a new trifocal IOL with PanOptix Pro IOL in cataract surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Participants with bilateral cataracts will have sequential cataract surgery, receiving the investigational LPYWT0 trifocal IOL in one eye and the commercially available PXYWT0 PanOptix Pro trifocal IOL in the other eye, about 7–14 days apart. The trial plans about 9 visits over roughly 7 months to compare visual outcomes between the two eyes. The study is conducted in India and the Philippines and aims to characterize the visual performance of the LPYWT0 IOL relative to a marketed trifocal lens.

Why it matters

Who can join: the full rules

Key Inclusion Criteria:

* The calculated power needed for the artificial lens (IOL) must be between +15.0 and +25.0 D in each eye, designed to bring subject vision as close to "0.0" (neutral) as possible, meaning they will not be strongly nearsighted or farsighted after surgery.
* Subjects must have low levels of astigmatism (misshapen cornea) in the eyes (less than 1.00 D).
* In the doctor's opinion, the subjects have the potential to achieve good vision (0.2 logMAR, which is roughly 20/32 Snellen or better) in each eye after the surgery, when wearing the best possible spectacles or contact lenses.
* Other protocol-specified inclusion criteria may apply.

Key Exclusion Criteria:

* Clinically significant corneal diseases which may, according to the investigator's medical opinion, adversely affect visual outcomes.
* Any ocular or systemic health condition or medical issue that, in the investigator's medical opinion, could make the study results unreliable, prevent the person from finishing the study, or increase their safety risk.
* People who want to have one eye set for distance vision and the other for near vision.
* The doctor expects significant blurry vision (astigmatism) after the procedure.
* Other protocol-specified exclusion criteria may apply.

Where it's running

• Asian Eye Institute
  Makati City, Philippines Recruiting
• Personaleyes
  Sydney, New South Wales, Australia Not yet recruiting
• Dr. Agarwal's Eye Hospital Limited
  Chennai, Tamil Nadu, India Not yet recruiting
• Narayana Nethralaya
  Bangalore, India Not yet recruiting
• Peregrine Eye Laser and Institute
  Makati City, Manila, Philippines Not yet recruiting

Study contacts

• Study coordinator: Alcon Call Center
• Email: alcon.medinf@alcon.com
• Phone: 1-888-451-3937

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.