Anterior segment anatomy assessment with swept-source OCT in eye surgery patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective observational study at Nanfang Hospital that uses swept-source OCT to measure ocular anatomical parameters before and after anterior segment surgeries. The goal is to describe how anatomy varies across patients and surgery types, and to explore links with clinical factors. Data will include demographic information and surgical details, with imaging performed using a CASIA2 device. Analyses will focus on the distribution of anatomical measurements and potential differences among surgical subgroups. The study will help improve understanding of patient-specific anterior segment anatomy in the surgical setting.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Voluntary provision of written informed consent.
* 18≤Age≤90 years.
* Patients diagnosed by an ophthalmologist with cataract, primary angle-closure disease, or other anterior segment disorders requiring anterior segment surgery.
* Availability of complete or accessible preoperative and postoperative clinical records and ophthalmic examination data.

Exclusion Criteria:

* Follow-up duration of less than 3 months.
* Substantial missing ophthalmic examination or perioperative data that prevents the required study analyses.
* Inability to obtain valid anterior segment imaging data due to severe corneal opacity, poor ocular fixation, inadequate cooperation, or other related factors.
* Presence of severe ocular trauma, intraocular tumors, severe corneal disease, active intraocular inflammation, or other ocular conditions that may substantially affect anterior segment structural assessment.
* History of complex intraocular surgery that may significantly alter anterior segment anatomy and is considered unsuitable for inclusion by the investigator.
* Other conditions considered by the investigator to make the patient unsuitable for participation in the study.

Where it's running

• Nanfang Hospital, Southern Medical University
  Guangzhou, Guangdong, China Recruiting

Study contacts

• Study coordinator: Hongyang Zhang
• Email: zengli729600@163.com
• Phone: 13503005716

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.