Comparing two techniques for total knee prosthesis installation
Mechanically or Kinematically Aligned Total Knee Prosthesis: Prospective and Comparative Study of Clinical, Stereoradiographic, and Biomechanical Results
This study is testing two different ways to install knee replacements to see which method helps patients feel better and have fewer problems after surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Clinique du Sport, Bordeaux Mérignac Academic / other |
| Locations | 1 site (Mérignac) |
| Trial ID | NCT06158646 on ClinicalTrials.gov |
What this trial studies
This study compares two techniques for total knee prosthesis installation: Mechanical Alignment (MA) and Kinematic Alignment (KA). The MA technique uses fixed angles for bone cuts, which may lead to residual symptoms and dissatisfaction in patients. In contrast, the KA technique aims to restore the unique pre-arthritic anatomy of each knee, potentially improving clinical outcomes. The study will evaluate the effectiveness of these approaches in patients who have undergone total knee arthroplasty.
Who should consider this trial
Good fit: Ideal candidates are adults who have undergone total knee arthroplasty and are being followed up one year post-surgery.
Not a fit: Patients with a contralateral knee prosthesis or other significant lower limb conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved patient satisfaction and reduced residual symptoms after total knee replacement.
How similar studies have performed: Previous studies have shown promising results with kinematic alignment techniques, suggesting potential for improved outcomes compared to traditional methods.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient followed as part of a consultation 1 year after TKA placement * Adult patient * Patient affiliated to a social security system * Patient informed of the study and formally included (signing of informed consent) before the first research review Exclusion Criteria: * Patient with a contralateral knee prosthesis * Patient with another condition (acquired pathology) of the lower limbs (e.g. severe osteoarthritis of the contralateral knee or hip/ankle) and/or of the nervous system (e.g. Parkinson's) which may significantly affect the quality of walking * Pregnant patient * Patient deprived of liberty by judicial or administrative decision, * Adult patient subject to a legal protection measure or unable to express consent
Where this trial is running
Mérignac
- Clinique du Sport Bordeaux Merignac — Mérignac, France (Recruiting)
Study contacts
- Study coordinator: Charles Rivière, MD
- Email: charles.riviere@bari-arthroplasty.com
- Phone: +33 5 56 46 10 40
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.