Comparing two pain relief techniques for kidney surgery
Official title: Analgesic Efficacy of Ultrasound-guided External Oblique Intercostal Plane Block Versus Posterior Transversus Abdominis Plane Block in Patients Undergoing Open Nephrectomy: A Randomized Double-blinded Comparative Study
Run by Cairo University · NCT06892743 · Data updated 2026-11-12
This study is testing two different pain relief methods for kidney surgery to see which one helps patients feel better and need fewer pain medications after their operation.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 56 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 2 sites (Maadi, Cairo Governorate and 1 other locations) |
| Status | Recruiting |
| Started | April 1, 2025 |
| Main results expected | July 2026 |
| Study ends | August 2026 |
| Registry record updated | June 1, 2026 |
| Trial ID | NCT06892743 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 to 65 with renal carcinoma scheduled for open nephrectomy and classified as ASA class II-III.
✕Probably not a fit
Patients with hepatic or renal insufficiency, unstable cardiovascular or pulmonary disease, or those on regular opioid consumption may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of two ultrasound-guided nerve block techniques, the external oblique intercostal plane block (EOIPB) and the posterior transversus abdominis plane block, in managing postoperative pain for patients undergoing open nephrectomy due to renal cell carcinoma. The aim is to determine which technique provides better analgesia and reduces the need for opioids, thereby minimizing side effects and improving recovery outcomes. Patients will be monitored for pain levels and any complications following surgery.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing kidney surgery, enhancing recovery and reducing reliance on opioids.
How similar studies have gone: Other studies have shown promising results with ultrasound-guided nerve blocks for postoperative pain management, indicating that this approach is gaining traction in clinical practice.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients whom diagnosed as having renal carcinoma and scheduled for open nephrectomy under general anesthesia. * ASA class II- III. * Age ≥ 18 and ≤ 70 years. * Body mass index (BMI) less than 40kg/m2. Exclusion Criteria: 1. Patient refusal. 2. Hepatic and renal insufficiency. 3. Unstable cardiovascular or pulmonary disease. 4. History of psychiatric and cognitive disorders. 5. Patients with known sensitivity or contraindications to the drug used. 6. Patients on regular opioid consumption.
Where it's running
-
Kasr Alainy Faculty of Medicine - Cairo university
Cairo, Egypt Recruiting -
Abeer Ahmed Mohamed
Maadi, Cairo Governorate, Egypt Completed
Study contacts
- Study coordinator: Abeer A Mohamed
- Email: abeer_ahmed@kasralainy.edu.eg
- Phone: 01005244590
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.