Comparing two pain relief techniques for kidney surgery
Analgesic Efficacy of Ultrasound-guided External Oblique Intercostal Plane Block Versus Posterior Transversus Abdominis Plane Block in Patients Undergoing Open Nephrectomy: A Randomized Double-blinded Comparative Study
This study is testing two different pain relief methods for kidney surgery to see which one helps patients feel better and need fewer pain medications after their operation.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 56 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Cairo University Academic / other |
| Locations | 2 sites (Maadi, Cairo Governorate and 1 other locations) |
| Trial ID | NCT06892743 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of two ultrasound-guided nerve block techniques, the external oblique intercostal plane block (EOIPB) and the posterior transversus abdominis plane block, in managing postoperative pain for patients undergoing open nephrectomy due to renal cell carcinoma. The aim is to determine which technique provides better analgesia and reduces the need for opioids, thereby minimizing side effects and improving recovery outcomes. Patients will be monitored for pain levels and any complications following surgery.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 65 with renal carcinoma scheduled for open nephrectomy and classified as ASA class II-III.
Not a fit: Patients with hepatic or renal insufficiency, unstable cardiovascular or pulmonary disease, or those on regular opioid consumption may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing kidney surgery, enhancing recovery and reducing reliance on opioids.
How similar studies have performed: Other studies have shown promising results with ultrasound-guided nerve blocks for postoperative pain management, indicating that this approach is gaining traction in clinical practice.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients whom diagnosed as having renal carcinoma and scheduled for open nephrectomy under general anesthesia. * ASA class II- III. * Age ≥ 18 and ≤ 65 years. * Body mass index (BMI) less than 40kg/m2. Exclusion Criteria: * 1\. Patient refusal. 2. Hepatic and renal insufficiency. 3. Unstable cardiovascular or pulmonary disease. 4. History of psychiatric and cognitive disorders. 5. Patients with known sensitivity or contraindications to the drug used. 6. Patients on regular opioid consumption.
Where this trial is running
Maadi, Cairo Governorate and 1 other locations
- Abeer Ahmed Mohamed — Maadi, Cairo Governorate, Egypt (Recruiting)
- Kasr Alainy Faculty of Medicine - Cairo university — Cairo, Egypt (Recruiting)
Study contacts
- Study coordinator: Abeer A Mohamed
- Email: abeer_ahmed@kasralainy.edu.eg
- Phone: 01005244590
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.