Clinical trial Recruiting at 1 site Interventional Ages 18 to 70

Comparing two pain relief techniques for kidney surgery

Official title: Analgesic Efficacy of Ultrasound-guided External Oblique Intercostal Plane Block Versus Posterior Transversus Abdominis Plane Block in Patients Undergoing Open Nephrectomy: A Randomized Double-blinded Comparative Study

Run by Cairo University · NCT06892743 · Data updated 2026-11-12

This study is testing two different pain relief methods for kidney surgery to see which one helps patients feel better and need fewer pain medications after their operation.

Quick facts

Study typeInterventional
Ages18 Years to 70 Years
SexAll
Enrollment56 (estimated)
SponsorCairo University
Academic / other
Locations2 sites (Maadi, Cairo Governorate and 1 other locations)
StatusRecruiting
StartedApril 1, 2025
Main results expectedJuly 2026
Study endsAugust 2026
Registry record updatedJune 1, 2026
Trial IDNCT06892743 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 to 65 with renal carcinoma scheduled for open nephrectomy and classified as ASA class II-III.

Probably not a fit

Patients with hepatic or renal insufficiency, unstable cardiovascular or pulmonary disease, or those on regular opioid consumption may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of two ultrasound-guided nerve block techniques, the external oblique intercostal plane block (EOIPB) and the posterior transversus abdominis plane block, in managing postoperative pain for patients undergoing open nephrectomy due to renal cell carcinoma. The aim is to determine which technique provides better analgesia and reduces the need for opioids, thereby minimizing side effects and improving recovery outcomes. Patients will be monitored for pain levels and any complications following surgery.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing kidney surgery, enhancing recovery and reducing reliance on opioids.

How similar studies have gone: Other studies have shown promising results with ultrasound-guided nerve blocks for postoperative pain management, indicating that this approach is gaining traction in clinical practice.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients whom diagnosed as having renal carcinoma and scheduled for open nephrectomy under general anesthesia.
* ASA class II- III.
* Age ≥ 18 and ≤ 70 years.
* Body mass index (BMI) less than 40kg/m2.

Exclusion Criteria:

1. Patient refusal.
2. Hepatic and renal insufficiency.
3. Unstable cardiovascular or pulmonary disease.
4. History of psychiatric and cognitive disorders.
5. Patients with known sensitivity or contraindications to the drug used.
6. Patients on regular opioid consumption.

Where it's running

  • Kasr Alainy Faculty of Medicine - Cairo university
    Cairo, Egypt
    Recruiting
  • Abeer Ahmed Mohamed
    Maadi, Cairo Governorate, Egypt
    Completed

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.