Comparing two pain management techniques for liver surgery
Official title: Retrolaminar Block Versus Subcostal Transversus Abdominis Plane Block in Patients Undergoing Open Liver Resection Surgery
Run by Cairo University · NCT06621472 · Data updated 2026-11-12
This study is testing which pain management technique, either the retrolaminar block or the subcostal TAP block, works better for people having liver surgery to help them feel less pain and recover faster.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 90 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo) |
| Status | Recruiting |
| Started | October 1, 2024 |
| Main results expected | January 1, 2027 |
| Study ends | January 1, 2027 |
| Registry record updated | September 1, 2026 |
| Trial ID | NCT06621472 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients with ASA physical status II or III and a BMI between 20 and 35 kg/m2 who are scheduled for open liver resection.
✕Probably not a fit
Patients with severe respiratory, cardiac disorders, renal disease, or contraindications to regional anesthesia may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study compares the effectiveness of the retrolaminar block (RLB) and the subcostal transversus abdominis plane (TAP) block for pain management in patients undergoing open liver resection surgery. Both techniques aim to provide adequate analgesia and reduce opioid consumption postoperatively. The RLB is a modified paravertebral block that uses ultrasound guidance to deliver local anesthetic, while the TAP block targets specific nerves in the abdominal region. The goal is to determine which method offers better pain control and recovery outcomes.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing liver surgery, enhancing their recovery experience.
How similar studies have gone: Previous studies have shown success with similar regional anesthesia techniques, indicating potential for effective pain management in surgical settings.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Physical status American Society of Anesthesiologists (ASA)II, III. Body mass index (BMI): 20-35 kg/m2. Exclusion Criteria: Patient refusal Physical status ASA IV BMI \< 20 kg/m2 and \>35 kg/m2 known sensitivity or contraindication to drug used in the study (local anesthetics, opioids). History of psychological disorders and/or chronic pain. Contraindication to regional anesthesia e.g., local sepsis, pre- existing peripheral neuropathies, and coagulopathy. Severe respiratory, cardiac disorders and renal disease.
Where it's running
-
Cairo University
Cairo, Egypt Recruiting
Study contacts
- Principal investigator: sayed M Abed — Cairo University
- Study coordinator: sayed M abed, MD degree
- Email: sydabed2020@outlook.com
- Phone: 1226806532
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.