Clinical trial Recruiting at 1 site Interventional Ages 18 to 65

Comparing two pain management techniques for liver surgery

Official title: Retrolaminar Block Versus Subcostal Transversus Abdominis Plane Block in Patients Undergoing Open Liver Resection Surgery

Run by Cairo University · NCT06621472 · Data updated 2026-11-12

This study is testing which pain management technique, either the retrolaminar block or the subcostal TAP block, works better for people having liver surgery to help them feel less pain and recover faster.

Quick facts

Study typeInterventional
Ages18 Years to 65 Years
SexAll
Enrollment90 (estimated)
SponsorCairo University
Academic / other
Locations1 site (Cairo)
StatusRecruiting
StartedOctober 1, 2024
Main results expectedJanuary 1, 2027
Study endsJanuary 1, 2027
Registry record updatedSeptember 1, 2026
Trial IDNCT06621472 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients with ASA physical status II or III and a BMI between 20 and 35 kg/m2 who are scheduled for open liver resection.

Probably not a fit

Patients with severe respiratory, cardiac disorders, renal disease, or contraindications to regional anesthesia may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study compares the effectiveness of the retrolaminar block (RLB) and the subcostal transversus abdominis plane (TAP) block for pain management in patients undergoing open liver resection surgery. Both techniques aim to provide adequate analgesia and reduce opioid consumption postoperatively. The RLB is a modified paravertebral block that uses ultrasound guidance to deliver local anesthetic, while the TAP block targets specific nerves in the abdominal region. The goal is to determine which method offers better pain control and recovery outcomes.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing liver surgery, enhancing their recovery experience.

How similar studies have gone: Previous studies have shown success with similar regional anesthesia techniques, indicating potential for effective pain management in surgical settings.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Physical status American Society of Anesthesiologists (ASA)II, III. Body mass index (BMI): 20-35 kg/m2.

Exclusion Criteria:

Patient refusal Physical status ASA IV BMI \< 20 kg/m2 and \>35 kg/m2 known sensitivity or contraindication to drug used in the study (local anesthetics, opioids).

History of psychological disorders and/or chronic pain. Contraindication to regional anesthesia e.g., local sepsis, pre- existing peripheral neuropathies, and coagulopathy.

Severe respiratory, cardiac disorders and renal disease.

Where it's running

  • Cairo University
    Cairo, Egypt
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.