Clinical trial Recruiting at 1 site Interventional Ages 40 and up

Comparing two methods for calculating intraocular lens power during cataract surgery

Official title: Intraoperative Aberrometry vs Conventional Introcular Lens Calculation ( Barrett Universal II / Barrett True K ), Refractive and Visual Outcomes, a Prospective Study.

Run by Instituto de Oftalmología Fundación Conde de Valenciana · NCT06219252 · Data updated 2026-11-12

This study tests which method, using a special device during surgery or a formula before surgery, does a better job at calculating the right lens power for people getting cataract surgery.

Quick facts

Study typeInterventional
Ages40 Years and up
SexAll
Enrollment300 (estimated)
SponsorInstituto de Oftalmología Fundación Conde de Valenciana
Academic / other
Locations1 site (Mexico City, Cuauhtemoc)
StatusRecruiting
StartedNovember 3, 2023
Main results expectedNovember 30, 2026
Study endsDecember 31, 2026
Registry record updatedMay 14, 2025
Trial IDNCT06219252 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include patients with senile cataract who are scheduled for phacoemulsification and have a complete biometric profile.

Probably not a fit

Patients with glaucoma, uncontrolled diabetic retinopathy, or other significant ocular pathologies may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This intervention compares the accuracy of intraoperative aberrometry (ORA) against the Barrett Universal II preoperative calculation for determining intraocular lens power in patients undergoing cataract surgery. The study will involve randomization and blinding of participants to ensure unbiased results. Researchers will assess changes in spherical equivalent and uncorrected distance visual acuity at 90 days post-surgery to evaluate the effectiveness of each method.

Why it matters

Potential benefit: If successful, this study could lead to improved visual outcomes for patients undergoing cataract surgery.

How similar studies have gone: Previous studies have shown small differences between intraoperative aberrometry and preoperative calculations, indicating that this approach has been explored but may still offer novel insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patients with senile cataract, patients undergoing phacoemulsification, complete biometric profile, axial length calculated by interferometer.

Exclusion Criteria:

* glaucoma, uncontrolled diabetic retinopathy, pseudoexfoliation syndrome, aged macular degeneration , dry eye syndrome, other ocular pathologies.

Where it's running

  • Instituto de oftalmología Fundación Conde de Valenciana
    Mexico City, Cuauhtemoc, Mexico
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.