Comparing two methods for calculating intraocular lens power during cataract surgery

Intraoperative Aberrometry vs Conventional Introcular Lens Calculation ( Barrett Universal II / Barrett True K ), Refractive and Visual Outcomes, a Prospective Study.

Not applicable Interventional Instituto de Oftalmología Fundación Conde de Valenciana · NCT06219252

This study tests which method, using a special device during surgery or a formula before surgery, does a better job at calculating the right lens power for people getting cataract surgery.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment300 (estimated)
Ages40 Years and up
SexAll
SponsorInstituto de Oftalmología Fundación Conde de Valenciana Academic / other
Locations1 site (Mexico City, Cuauhtemoc)
Trial IDNCT06219252 on ClinicalTrials.gov

What this trial studies

This intervention compares the accuracy of intraoperative aberrometry (ORA) against the Barrett Universal II preoperative calculation for determining intraocular lens power in patients undergoing cataract surgery. The study will involve randomization and blinding of participants to ensure unbiased results. Researchers will assess changes in spherical equivalent and uncorrected distance visual acuity at 90 days post-surgery to evaluate the effectiveness of each method.

Who should consider this trial

Good fit: Ideal candidates include patients with senile cataract who are scheduled for phacoemulsification and have a complete biometric profile.

Not a fit: Patients with glaucoma, uncontrolled diabetic retinopathy, or other significant ocular pathologies may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved visual outcomes for patients undergoing cataract surgery.

How similar studies have performed: Previous studies have shown small differences between intraoperative aberrometry and preoperative calculations, indicating that this approach has been explored but may still offer novel insights.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patients with senile cataract, patients undergoing phacoemulsification, complete biometric profile, axial length calculated by interferometer.

Exclusion Criteria:

* glaucoma, uncontrolled diabetic retinopathy, pseudoexfoliation syndrome, aged macular degeneration , dry eye syndrome, other ocular pathologies.

Where this trial is running

Mexico City, Cuauhtemoc

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Intraocular Lens ImplantationCataractHumansOcular, Refractionbiometryaberrometryprospective study
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.