Comparing Sucrosomial Iron and Oral Iron for Treating Anemia in Ulcerative Colitis
Official title: Randomized Controlled Trial of Sucrosomial Iron vs. Oral Iron Sulfate for the Treatment of Iron Deficiency Anemia in Patients With Ulcerative Colitis
Run by American University of Beirut Medical Center · NCT05225545 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study tests if a new type of iron supplement called Sucrosomial Iron works better and is easier to tolerate than regular Oral Iron for adults with anemia caused by Ulcerative Colitis.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | American University of Beirut Medical Center Academic / other |
| Locations | 1 site (Beirut) |
| Trial ID | NCT05225545 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 with a confirmed diagnosis of Ulcerative Colitis and proven Iron Deficiency Anemia.
✕Probably not a fit
Patients who may not benefit from this study include those with severe anemia (Hb < 8g/dl), recent disease flare, or known intolerances to oral iron therapy.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to evaluate the tolerability and efficacy of Sucrosomial Iron compared to Oral Iron Therapy in patients suffering from Iron Deficiency Anemia associated with Ulcerative Colitis. It is a randomized controlled trial that focuses on patients over 18 years old who have been diagnosed with Ulcerative Colitis and have confirmed Iron Deficiency Anemia. The study will assess how well Sucrosomial Iron, a new iron preparation with better absorption and fewer side effects, performs against traditional Oral Iron supplementation, which can exacerbate symptoms in these patients.
Why it matters
Potential benefit: If successful, this study could provide a safer and more effective treatment option for patients with Iron Deficiency Anemia related to Ulcerative Colitis.
How similar studies have gone: Other studies have shown promising results with Sucrosomial Iron in various patient populations, suggesting potential for success in this specific application.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age above 18 * Confirmed diagnosis of Ulcerative Colitis * Proven Iron Deficiency Anemia (Hb \< 12 for females and Hb \< 13 for males AND iron saturation \<20%) * Hemoglobin level \> 8g/dl Exclusion Criteria: * Age below 18 * Hemoglobin level \< 8g/dl * Recently hospitalized for disease flare (within 3 months) * Hemoglobinopathies (including thalassemia) * Isolated proctitis * Indeterminate colitis * Known liver or kidney disease * Known Celiac Disease * Extensive small bowel resection * Use of anticoagulants or aspirin * Known intolerance to oral iron therapy * Uninvestigated anemia * Pregnant or lactating women * Known hypersensitivity to iron sulfate * Transfusion in the past 4 weeks * Erythropoetin within the last 8 weeks * Rheumatoid Arthritis * History of menometrorrhagia or frequent epistaxis
Where it's running
-
American University of Beirut - Medical Center
Beirut, Lebanon Recruiting
Study contacts
- Principal investigator: Ala Sharara, MD — American University of Beirut Medical Center
- Study coordinator: Ali El Mokahal, MD
- Email: ae136@aub.edu.lb
- Phone: +961350000
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Innovative Multidisciplinary and Virtual Care for IBD in Pregnancy
This study tests a dedicated IBD pregnancy care model, including a new virtual approach, to see if it improves access and quality of care for pregnant people with Crohn's disease or ulcerative colitis.
-
A Probiotic Approach to Modulating Gut Microbiota in Mild-to-Moderate Ulcerative Colitis
A specific probiotic given rectally will be tested in adults with mild-to-moderate ulcerative colitis to see if it can help manage symptoms.
-
Advanced therapies for moderately to severely active Crohn's disease or ulcerative colitis in adults
This study tests combinations of risankizumab with either trosunilimab or ABBV-701 in adults with moderately to severely active Crohn's disease or ulcerative colitis.
-
Longitudinal Immunophenotyping of People with Inflammatory Bowel Disease
This study will follow adults with Crohn's disease or ulcerative colitis (and some healthy relatives) over three years to see how their immune cells change over time and how genetics and diet relate to their disease.
-
High Protein, High Fiber Diet for Ulcerative Colitis
This study tests a high-protein, high-fiber diet to see if it helps people with ulcerative colitis by meeting protein needs and lowering harmful hydrogen sulfide production in the gut.
-
Ath-063: Testing a new treatment for moderately to severely active ulcerative colitis in patients who have tried other biologics
This study tests ATH-063 to see if it helps people with moderate to severe ulcerative colitis who did not respond to or relapsed after prior biologic therapy.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.