Comparing stitching techniques to reduce hernias after kidney transplants
The Impact of Abdominal Wall Closure Technique on Incidence of Incisional Hernia in Kidney Transplantation
This study is testing whether using smaller stitches instead of larger ones during kidney transplant surgery can help reduce the chance of hernias in patients.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Manchester University NHS Foundation Trust Government |
| Locations | 1 site (Manchester) |
| Trial ID | NCT03959904 on ClinicalTrials.gov |
What this trial studies
This study investigates the impact of different abdominal wall closure techniques on the incidence of incisional hernias in kidney transplant patients. It consists of two phases: the first phase involves a retrospective review of hernia incidence and risk factors in the transplant population over the past decade. The second phase is a prospective randomized blinded trial comparing the conventional large bites technique with a smaller bites technique for closing abdominal incisions. The goal is to determine if smaller stitches can reduce the risk of hernia formation in these patients.
Who should consider this trial
Good fit: Ideal candidates for this study are patients aged 18-70 with end-stage renal failure undergoing their first or second kidney transplant.
Not a fit: Patients outside the age range or those with previous transplants that have left a scar in the iliac fossa may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly reduce the incidence of incisional hernias in kidney transplant patients, improving their recovery and quality of life.
How similar studies have performed: Other studies have shown success with similar approaches in reducing hernia rates in various surgical populations, suggesting potential for this method in kidney transplantation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * End-stage renal failure patients * Aged 18-70yrs * First transplants or second transplants * Ability to adequately understand English and consent for study * BMI\<35 kg/m2) * Living donor nephrectomy patients Exclusion Criteria * Outside age range, * Previous transplants which have left a scar in the ilia fossa
Where this trial is running
Manchester
- Manchester University NHS Foundation Trust — Manchester, United Kingdom (Recruiting)
Study contacts
- Study coordinator: Alex Shaw
- Email: alex.shaw@mft.nhs.uk
- Phone: +441617012066
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.