Clinical trial Recruiting at 1 site Interventional Ages 18 to 70

Comparing stitching techniques to reduce hernias after kidney transplants

Official title: The Impact of Abdominal Wall Closure Technique on Incidence of Incisional Hernia in Kidney Transplantation

Run by Manchester University NHS Foundation Trust · NCT03959904 · Data updated 2026-11-12

This study is testing whether using smaller stitches instead of larger ones during kidney transplant surgery can help reduce the chance of hernias in patients.

Quick facts

Study typeInterventional
Ages18 Years to 70 Years
SexAll
Enrollment50 (estimated)
SponsorManchester University NHS Foundation Trust
Government
Locations1 site (Manchester)
StatusRecruiting
StartedMarch 10, 2020
Main results expectedJune 30, 2026
Study endsJune 30, 2026
Registry record updatedMay 9, 2025
Trial IDNCT03959904 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients aged 18-70 with end-stage renal failure undergoing their first or second kidney transplant.

Probably not a fit

Patients outside the age range or those with previous transplants that have left a scar in the iliac fossa may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the impact of different abdominal wall closure techniques on the incidence of incisional hernias in kidney transplant patients. It consists of two phases: the first phase involves a retrospective review of hernia incidence and risk factors in the transplant population over the past decade. The second phase is a prospective randomized blinded trial comparing the conventional large bites technique with a smaller bites technique for closing abdominal incisions. The goal is to determine if smaller stitches can reduce the risk of hernia formation in these patients.

Why it matters

Potential benefit: If successful, this study could significantly reduce the incidence of incisional hernias in kidney transplant patients, improving their recovery and quality of life.

How similar studies have gone: Other studies have shown success with similar approaches in reducing hernia rates in various surgical populations, suggesting potential for this method in kidney transplantation.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* End-stage renal failure patients
* Aged 18-70yrs
* First transplants or second transplants
* Ability to adequately understand English and consent for study
* BMI\<35 kg/m2)
* Living donor nephrectomy patients Exclusion Criteria
* Outside age range,
* Previous transplants which have left a scar in the ilia fossa

Where it's running

  • Manchester University NHS Foundation Trust
    Manchester, United Kingdom
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.