Comparing stitching techniques to reduce hernias after kidney transplants
Official title: The Impact of Abdominal Wall Closure Technique on Incidence of Incisional Hernia in Kidney Transplantation
Run by Manchester University NHS Foundation Trust · NCT03959904 · Data updated 2026-11-12
This study is testing whether using smaller stitches instead of larger ones during kidney transplant surgery can help reduce the chance of hernias in patients.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Manchester University NHS Foundation Trust Government |
| Locations | 1 site (Manchester) |
| Status | Recruiting |
| Started | March 10, 2020 |
| Main results expected | June 30, 2026 |
| Study ends | June 30, 2026 |
| Registry record updated | May 9, 2025 |
| Trial ID | NCT03959904 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients aged 18-70 with end-stage renal failure undergoing their first or second kidney transplant.
✕Probably not a fit
Patients outside the age range or those with previous transplants that have left a scar in the iliac fossa may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the impact of different abdominal wall closure techniques on the incidence of incisional hernias in kidney transplant patients. It consists of two phases: the first phase involves a retrospective review of hernia incidence and risk factors in the transplant population over the past decade. The second phase is a prospective randomized blinded trial comparing the conventional large bites technique with a smaller bites technique for closing abdominal incisions. The goal is to determine if smaller stitches can reduce the risk of hernia formation in these patients.
Why it matters
Potential benefit: If successful, this study could significantly reduce the incidence of incisional hernias in kidney transplant patients, improving their recovery and quality of life.
How similar studies have gone: Other studies have shown success with similar approaches in reducing hernia rates in various surgical populations, suggesting potential for this method in kidney transplantation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * End-stage renal failure patients * Aged 18-70yrs * First transplants or second transplants * Ability to adequately understand English and consent for study * BMI\<35 kg/m2) * Living donor nephrectomy patients Exclusion Criteria * Outside age range, * Previous transplants which have left a scar in the ilia fossa
Where it's running
-
Manchester University NHS Foundation Trust
Manchester, United Kingdom Recruiting
Study contacts
- Study coordinator: Alex Shaw
- Email: alex.shaw@mft.nhs.uk
- Phone: +441617012066
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.