Comparing pain management methods for ACL surgery

Comparison of Preemptive Multimodal Analgesia and Femoral Triangle Block on Early Rehabilitation in ACL Reconstruction: A Prospective, Randomized, Double-Blind Study

NA · Ankara University · NCT06936995

This study is testing whether a new way of managing pain before ACL surgery works better than a traditional method to help patients recover more comfortably.

Quick facts

PhaseNA
Study typeInterventional
Enrollment62 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorAnkara University (other)
Locations1 site (Ankara)
Trial IDNCT06936995 on ClinicalTrials.gov

What this trial studies

This study compares the effectiveness of a preemptive multimodal intravenous analgesia protocol versus a femoral triangle block for managing postoperative pain in patients undergoing anterior cruciate ligament (ACL) reconstruction. Adult patients aged 18 to 65 will be randomly assigned to receive one of the two pain management techniques before surgery. The study will evaluate rehabilitation compliance through various tests and pain scores at multiple postoperative time points, while also assessing secondary outcomes like opioid consumption and side effects. The goal is to determine which method better supports early rehabilitation and reduces pain.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 to 65 scheduled for ACL reconstruction surgery.

Not a fit: Patients with a BMI of 30 kg/m² or higher, those with allergies to local anesthetics, or those with chronic pain conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies that enhance rehabilitation outcomes for ACL surgery patients.

How similar studies have performed: Previous studies have shown that multimodal analgesia can lead to better pain control and patient satisfaction compared to single-modality approaches, indicating potential success for this study.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Age: 18 years or older. Condition: Patients scheduled for anterior cruciate ligament (ACL) reconstruction surgery.

ASA Classification: Patients classified as ASA I, II, or III. Orientation: Patients who are fully oriented and can cooperate with study procedures.

Consent: Patients capable of providing informed consent to participate in the study.

Exclusion Criteria:

Informed Consent: Patients unable to provide informed consent. BMI: Patients with a BMI of ≥30 kg/m². Allergy: Known allergy to local anesthetics. Orientation and Cooperation: Patients who are not fully oriented or cannot cooperate with study procedures.

Additional Trauma: Patients with other traumatic injuries requiring opioid analgesia.

Neuropathic Pain History: Patients with a history of neuropathic pain. Chronic Pain Syndrome: Patients with a history of chronic pain syndrome.

Where this trial is running

Ankara

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Anterior Cruciate Ligament Injuries, Postoperative Pain, Pain, Postoperative, Anterior Cruciate Ligament Reconstruction, Postoperative Pain Management, Multimodal Analgesia, Femoral Triangle Block, Rehabilitation Outcomes

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.