Comparing eccentric and traditional exercise on fatigue in multiple sclerosis
Official title: The Effect of Lower Extremity Eccentric Resistance Training on Fatigue in Multiple Sclerosis
Run by Hunter College of City University of New York · NCT06505421 · Data updated 2026-11-12
This study is testing whether eccentric exercise is better than traditional exercise for reducing fatigue in people with multiple sclerosis.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 75 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Hunter College of City University of New York Academic / other |
| Locations | 1 site (New York, New York) |
| Status | Recruiting |
| Started | July 1, 2024 |
| Main results expected | December 30, 2025 |
| Study ends | December 30, 2026 |
| Registry record updated | July 17, 2024 |
| Trial ID | NCT06505421 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals with a definitive diagnosis of multiple sclerosis who can walk for six minutes continuously.
✕Probably not a fit
Patients who have experienced a recent exacerbation of MS or have other orthopedic or cardiopulmonary conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to compare the effects of eccentric resistance training versus traditional resistance training on fatigue levels in individuals with multiple sclerosis (MS). Participants will engage in two different training sessions over two weeks, with one week dedicated to each type of training. After each session, fatigue levels will be assessed to determine any differences between the two training methods. The study seeks to understand if eccentric training, which may be less fatiguing, could be a viable option for improving mobility in MS patients.
Why it matters
Potential benefit: If successful, this study could provide insights into more effective exercise regimens for managing fatigue in patients with multiple sclerosis.
How similar studies have gone: While eccentric training has shown promise in other populations, this specific comparison in MS is novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Definitive diagnosis of Multiple Sclerosis. * Ability to walk for 6 minutes continuously with or without assistive device * Ability read, understand and sign and informed consent Exclusion Criteria: * Evidence of recent exacerbation in the last 2 months prior to starting the study * Orthopedic, cardiopulmonary, or non -MS neurologic condition that could interfere with carrying out the study protocol
Where it's running
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Hunter College, Physical Therapy Department, City University of New York
New York, New York, United States Recruiting
Study contacts
- Study coordinator: Herbert Karpatkin, DSc
- Email: hkarpatk@hunter.cuny.edu
- Phone: 212-396-7115
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.