Comparing eccentric and traditional exercise on fatigue in multiple sclerosis
The Effect of Lower Extremity Eccentric Resistance Training on Fatigue in Multiple Sclerosis
This study is testing whether eccentric exercise is better than traditional exercise for reducing fatigue in people with multiple sclerosis.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 30 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Hunter College of City University of New York Academic / other |
| Locations | 1 site (New York, New York) |
| Trial ID | NCT06505421 on ClinicalTrials.gov |
What this trial studies
This observational study aims to compare the effects of eccentric resistance training versus traditional resistance training on fatigue levels in individuals with multiple sclerosis (MS). Participants will engage in two different training sessions over two weeks, with one week dedicated to each type of training. After each session, fatigue levels will be assessed to determine any differences between the two training methods. The study seeks to understand if eccentric training, which may be less fatiguing, could be a viable option for improving mobility in MS patients.
Who should consider this trial
Good fit: Ideal candidates are individuals with a definitive diagnosis of multiple sclerosis who can walk for six minutes continuously.
Not a fit: Patients who have experienced a recent exacerbation of MS or have other orthopedic or cardiopulmonary conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into more effective exercise regimens for managing fatigue in patients with multiple sclerosis.
How similar studies have performed: While eccentric training has shown promise in other populations, this specific comparison in MS is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Definitive diagnosis of Multiple Sclerosis. * Ability to walk for 6 minutes continuously with or without assistive device * Ability read, understand and sign and informed consent Exclusion Criteria: * Evidence of recent exacerbation in the last 2 months prior to starting the study * Orthopedic, cardiopulmonary, or non -MS neurologic condition that could interfere with carrying out the study protocol
Where this trial is running
New York, New York
- Hunter College, Physical Therapy Department, City University of New York — New York, New York, United States (Recruiting)
Study contacts
- Study coordinator: Herbert Karpatkin, DSc
- Email: hkarpatk@hunter.cuny.edu
- Phone: 212-396-7115
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.