Comparing bone gain using 3D printed zirconia barriers and titanium mesh

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of customized 3D printed zirconia barriers compared to traditional titanium mesh in promoting bone gain in patients with combined ridge defects in the esthetic zone. The study involves a randomized design with 26 sites, where patients will be assigned to receive either the zirconia barrier or titanium mesh after thorough pre-operative assessments. The primary outcome is the amount of bone gained, measured both clinically and radiographically, following the procedure. The trial aims to address the complications associated with titanium mesh while exploring the potential benefits of zirconia in bone augmentation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age: 20-70 years.
* Bone width less than 4mm
* Vertical bone height less than 9mm
* Periodontally sound neighboring teeth
* Patients with sound vertical occlusal bite dimension
* Good oral hygiene (full mouth plaque control record \[PCR\] \< 25%,full mouth bleeding on probing (BOP) \< 25% .
* Patients demonstrating understanding and commitment to the post-operative care regime and the study follow up timeline.
* Good general health (including participants with well-controlled systemic disease)

Exclusion Criteria:

1. Pathological lesions (abscess-cyst-acute infection) in the defect site
2. Systemic diseases that would interfere with bone metabolism
3. Uncontrolled diabetic patients
4. Ongoing treatment or a history of recent chemotherapy or radiotherapy
5. Poor oral hygiene after hygienic phase (Plaque control record over 30%) or Active periodontal disease

Where it's running

• Cairo university
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Amaal Abdalnassar abdalzeim
• Email: amaalabdalnassar@gmail.com
• Phone: 01003752752

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Ridge splitting to widen the alveolar ridge with implant placement

  This study tests whether splitting a narrow alveolar ridge can widen bone and stabilize a placed dental implant in people with bone loss around the jaw.

  Recruiting Beni-Suef University · Cairo · NCT07664605

• Two bovine bone grafts in sinus lift with or without jaw marrow blood

  This study tests whether adding a small amount of jawbone marrow blood to two bovine bone grafts helps create more new bone and height in sinus lift surgery for adults needing implants.

  Recruiting Universidad del Desarrollo · Santiago, Santiago Metropolitan · NCT07904065

• Melatonin Gel in Immediate Molar Implants in the Back of the jaw

  In this small study, researchers test whether applying a 1% melatonin gel during immediate molar implant placement in the back of the lower jaw helps with healing and bone formation.

  Recruiting Future University in Egypt · Cairo · NCT07869030

• Bone marrow cells plus Bio-Oss graft for repairing severe jawbone defects

  This study tests whether using a patient’s own bone marrow–derived mononuclear cells mixed with Bio-Oss graft can repair severe maxillofacial bone defects in adults aged 18-60.

  Recruiting The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School · Nanjing, Jiangsu · NCT07852806

• Porous zirconia shell to widen the jawbone before implants

  A small group of adults with a narrow lower back jaw will try a custom porous zirconia shell placed over bone grafts to see if it helps form good-quality new bone before placing dental implants.

  Recruiting October University for Modern Sciences and Arts · Giza, Giza Governorate · NCT07841158

• Immediate molar implants with customized healing abutments in different socket classes

  This study tests placing an implant right after extracting a back tooth and using a custom healing cap to shape the gum from day one, in people needing posterior implants.

  Recruiting Plovdiv Medical University · Plovdiv · NCT07801573

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.