Combining exercise with intermittent fasting to improve eye dryness in pre-diabetic psoriasis patients
Official title: Effect of Addition of Pyramidal Exercise to Intermittent Fasting on Dryness of Eye in Pre-diabetic Psoriasis Patients
Run by Cairo University · NCT06893913 · Data updated 2026-11-12
This study is testing if combining exercise with intermittent fasting can help reduce eye dryness in people with psoriasis and prediabetes.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 45 Years to 55 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Giza, Dokki) |
| Status | Recruiting |
| Started | March 1, 2025 |
| Main results expected | September 1, 2025 |
| Study ends | September 1, 2025 |
| Registry record updated | March 25, 2025 |
| Trial ID | NCT06893913 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are obese individuals with chronic plaque psoriasis, prediabetes, and symptoms of dry eyes.
✕Probably not a fit
Patients with diabetes, hypertension, or significant cardiac, respiratory, renal, or hepatic issues may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effects of adding pyramidal exercise to an intermittent fasting regimen on alleviating eye dryness in obese patients suffering from chronic plaque psoriasis and prediabetes. Forty participants will be randomly assigned to either a group receiving only intermittent fasting or a group that combines intermittent fasting with pyramidal training exercises. The intermittent fasting will involve a 5:2 diet, where participants eat freely for five days and restrict calories on two non-consecutive days. The exercise component will consist of structured running sessions on a treadmill, supplemented with warm-up and cool-down activities, conducted three times a week for two weeks.
Why it matters
Potential benefit: If successful, this approach could significantly improve eye dryness and overall health in patients with psoriasis and prediabetes.
How similar studies have gone: While the combination of exercise and intermittent fasting is a novel approach, similar interventions have shown promise in improving metabolic and dermatological conditions.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * chronic plaque psoriasis * obesity class I * prediabetic persons * dryness of both eyes Exclusion Criteria: * cardiac insults * respiratory insults * diabetics hypertensives or renal, hepatic insults
Where it's running
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Faculty of physical therapy
Giza, Dokki, Egypt Recruiting
Study contacts
- Principal investigator: Ali MA Ismail, lecturer — Cairo University
- Study coordinator: Ali MA Isamil, Lecturer
- Email: ali.mohamed@pt.cu.edu.eg
- Phone: 0201005154209
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.