Combining exercise with intermittent fasting to improve eye dryness in pre-diabetic psoriasis patients

Effect of Addition of Pyramidal Exercise to Intermittent Fasting on Dryness of Eye in Pre-diabetic Psoriasis Patients

Not applicable Interventional Cairo University · NCT06893913

This study is testing if combining exercise with intermittent fasting can help reduce eye dryness in people with psoriasis and prediabetes.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages45 Years to 55 Years
SexAll
SponsorCairo University Academic / other
Locations1 site (Giza, Dokki)
Trial IDNCT06893913 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of adding pyramidal exercise to an intermittent fasting regimen on alleviating eye dryness in obese patients suffering from chronic plaque psoriasis and prediabetes. Forty participants will be randomly assigned to either a group receiving only intermittent fasting or a group that combines intermittent fasting with pyramidal training exercises. The intermittent fasting will involve a 5:2 diet, where participants eat freely for five days and restrict calories on two non-consecutive days. The exercise component will consist of structured running sessions on a treadmill, supplemented with warm-up and cool-down activities, conducted three times a week for two weeks.

Who should consider this trial

Good fit: Ideal candidates are obese individuals with chronic plaque psoriasis, prediabetes, and symptoms of dry eyes.

Not a fit: Patients with diabetes, hypertension, or significant cardiac, respiratory, renal, or hepatic issues may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve eye dryness and overall health in patients with psoriasis and prediabetes.

How similar studies have performed: While the combination of exercise and intermittent fasting is a novel approach, similar interventions have shown promise in improving metabolic and dermatological conditions.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* chronic plaque psoriasis
* obesity class I
* prediabetic persons
* dryness of both eyes

Exclusion Criteria:

* cardiac insults
* respiratory insults
* diabetics hypertensives or renal, hepatic insults

Where this trial is running

Giza, Dokki

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions PsoriasisPreDiabetesObesityDry Eye
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.