Clinical Decision Support to Help Treat Opioid Use Disorder

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study examines the impact of a clinical decision support alert that flags patients at risk for opioid use disorder when an opioid is prescribed. It provides providers with access to a clinical care pathway that offers screening guidance and treatment options, including medications for opioid use disorder. The project compares outcomes before and after implementing the CDS and pathway in real-world primary care settings. The intervention leverages existing guidelines to improve identification and management of OUD.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Primary care encounter AND
* Current opioid prescription (not buprenorphine) and Active opioid medications over the last 90 days OR
* Documented as on local Pain Registry "Does the patient fit the criteria to be included on the Pain Registry?" OR
* Has active problem list diagnosis of long-term (current) use of opiate analgesic OR
* Is taking \>=90 morphine milligram equivalents (MME) per day OR
* Prior positive toxicology screen for illicit drugs OR
* Diagnosis of opioid use disorder

Exclusion Criteria:

* Active cancer diagnosis in the last 1 year
* Hospice care/palliative care order
* Sickle cell disease diagnosis

Where it's running

• UCHealth
  Aurora, Colorado, United States Recruiting

Study contacts

• Principal investigator: Jason Hoppe, DO — University of Colorado, Denver
• Study coordinator: Heather Tolle, PhD
• Email: heather.tolle@cuanschutz.edu
• Phone: 303-724-9924

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Peer-led harm reduction intervention for opioid use disorder in hospitals

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• CBD for Opioid Dependence and Pain on Buprenorphine

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  Recruiting Early Phase 1 Yale University · West Haven, Connecticut · NCT07886606

• Cebranopadol for opioid withdrawal in adults with chronic pain

  This study tests whether cebranopadol can reduce withdrawal symptoms in adults with chronic pain who are physically dependent on prescribed opioids, compared with placebo.

  Recruiting at 2 sites Phase 2 Adneuris Therapeutics, Inc. · North Canton, Ohio and 1 other locations · NCT07874620

• emPath platform pilot to link and keep adults with opioid use disorder in care in Durham

  This pilot tests a mobile app and telemedicine approach to help adults with opioid use disorder start and stay in MOUD through community outreach in Durham, NC.

  Recruiting Duke University · Durham, North Carolina · NCT07810322

• CB1 Receptors in Opioid Use Disorder Measured with a PET Radioligand

  This study tests CB1 receptor availability in people with opioid use disorder starting opioid agonist therapy and compares them with healthy adults.

  Recruiting Phase 1 Yale University · New Haven, Connecticut · NCT07800520

• STORC: Training a support person plus patient navigation after birth

  We’re testing whether training a designated support person and using patient navigation after delivery helps people with opioid use disorder build recovery resources and stay in treatment.

  Recruiting Friends Research Institute, Inc. · Philadelphia, Pennsylvania · NCT07787039

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.