Choroidal venous flow changes after scleral buckle for retinal detachment
Official title: Choroidal Venous Congestion Following Scleral Buckling - An Imaging Study
Run by Singapore National Eye Centre · NCT07260097 · Data updated 2026-11-12
This project will use serial eye imaging to see if scleral buckle surgery changes choroidal blood flow and vessel structure in adults having their first retinal detachment repair.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 21 Years and up |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Singapore National Eye Centre Government |
| Locations | 1 site (Singapore) |
| Status | Recruiting |
| Started | July 17, 2025 |
| Main results expected | July 2028 |
| Study ends | July 2028 |
| Registry record updated | December 3, 2025 |
| Trial ID | NCT07260097 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 21 or older with a first retinal detachment in one eye planned for scleral buckle surgery (with or without vitrectomy or cataract surgery) and a clinically normal fellow eye who can give informed consent are ideal candidates.
✕Probably not a fit
Patients who have had prior intraocular surgery (other than cataract extraction with lens implant), who require other vitreoretinal procedures, who are pregnant or nursing, or who cannot give informed consent are unlikely to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Scleral buckle surgery places an external silicone band around the eye to support retinal breaks, and investigators hypothesize this may increase resistance in choroidal venous outflow. The study will follow patients who undergo scleral buckle (with or without vitrectomy or cataract surgery) using repeated imaging of the back of the eye to document quantitative and qualitative changes in choroidal vessels over time. Investigators expect initial alterations in vessel structure that progressively stabilize and may revert toward baseline with long-term remodeling. Findings will be compared opportunistically with the clinically normal fellow eye to characterize the pattern and time course of any venous congestion.
Why it matters
Potential benefit: If successful, the findings could improve understanding of how scleral buckle surgery affects choroidal blood flow and help inform better management of related retinal diseases such as AMD and PCV.
How similar studies have gone: While choroidal imaging has been applied in other retinal conditions, using serial imaging specifically to document venous congestion after scleral buckle is relatively novel and not yet widely validated.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 21 years and above * Ability to provide informed consent * First occurrence of a retinal detachment in one eye, deemed to require SB surgery with or without vitrectomy and/or cataract surgery. * Clinically normal fellow eye (no previous intraocular surgery except for cataract extraction with lens implant, intraocular laser or injection procedures). Exclusion Criteria: * Affected eye undergoing vitreoretinal procedure other than an SB surgery with or without vitrectomy and/or cataract surgery. * Pregnant or nursing women * Persons who are unable to give informed consent
Where it's running
-
Singapore Eye Research Institute
Singapore, Singapore Recruiting
Study contacts
- Study coordinator: Gemmy Cheung
- Email: gemmy.cheung.c.m@singhealth.com.sg
- Phone: +6563227460
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.