Chiropractic spinal manipulation for headaches
Official title: Chiropractic Spinal Manipulation for Cervicogenic and Tension-type Headache: a Pilot and Feasibility Study
Run by Real Centro Universitario Maria Cristina · NCT05240547 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is testing if chiropractic spinal manipulation can help reduce the intensity and frequency of chronic headaches in adults who have been suffering from them for at least three months.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 67 Years |
| Sex | All |
| Enrollment | 20 (estimated) |
| Sponsor | Real Centro Universitario Maria Cristina Academic / other |
| Locations | 1 site (San Lorenzo De El Escorial, Madrid) |
| Trial ID | NCT05240547 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 to 67 with a history of cervicogenic or tension-type headaches occurring at least twice a month for the past three months.
✕Probably not a fit
Patients with frequent migraine headaches or those with contraindications to spinal manipulation will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This pilot randomized controlled trial evaluates the effectiveness of chiropractic spinal manipulative therapy in treating chronic cervicogenic and tension-type headaches. Participants will receive either active spinal manipulation or a sham treatment over 8 sessions, with outcomes measured at various points throughout the study. The goal is to determine if chiropractic care can significantly reduce headache intensity and frequency compared to placebo. A total of 20 participants aged 18 to 67, experiencing headaches for at least 3 months, will be included in the study.
Why it matters
Potential benefit: If successful, this study could provide an effective non-pharmacological treatment option for patients suffering from chronic headaches.
How similar studies have gone: While there have been studies on chiropractic treatment for headaches, this specific approach focusing on cervicogenic and tension-type headaches is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * At least 2 episodes per month of cervicogenic or tension-type headache for at least 3 months. Diagnoses will be determined by case history and physical examination according to the International Headache Society criteria (3rd Edition) Exclusion Criteria: * Not fulfilling the inclusion criteria * Having received chiropractic treatment in the previous 12 months * Diagnosis or frequent symptoms of migraine headaches (symptoms present at least once a month) without an overlapping presentation of cervicogenic or tension-type headache. * Patients with pathologies affecting the nervous system (MS, tumors, past history of stroke...) * Contraindications to manual therapy, particularly spinal manipulative therapy (cancer, uncontrolled high blood-pressure, severe cardiovascular conditions) * Past history of cervical spine surgery * Pregnancy * Having being diagnosed with a psychiatric conditions, with the exception of depression and anxiety
Where it's running
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Real Centro Universitario María Cristina
San Lorenzo De El Escorial, Madrid, Spain Recruiting
Study contacts
- Principal investigator: Carlos Gevers Montoro, DC, MSc — RCU María Cristina
- Study coordinator: Elisa Torres Gonzalez, BSc
- Email: elisa.torres.quiro@gmail.com
- Phone: 918909435
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Post Isometric Relaxation vs Reciprocal Inhibition for Cervicogenic Headache
This study tests whether two gentle neck muscle techniques, post isometric relaxation and reciprocal inhibition, help people with cervicogenic headache more than a standard physical therapy routine.
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Kaltenborn vs Maitland Mobilization for Cervicogenic Headache
This trial tests whether Kaltenborn mobilization helps people with cervicogenic headache more than Maitland mobilization.
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Magnesium sulfate for acute non-traumatic headache in the ED: 2 g vs 4 g vs standard paracetamol
This study tests whether intravenous magnesium sulfate given in different doses helps adults with acute non-traumatic headache in the emergency department, compared with paracetamol.
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Physical profile of cervicogenic headache vs neck pain and healthy people
This observational study tests whether posture, grip strength, muscle stiffness, elasticity, and pressure sensitivity differ among people with cervicogenic headache, chronic neck pain, and healthy controls.
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Osteopathic manipulation versus physiotherapy for cervicocranial symptoms
This will test whether osteopathic manipulative treatment or standard physiotherapy reduces dizziness, headaches, and neck pain better in adults with cervicocranial dysfunction.
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Comparing two hands-on neck therapies for cervicogenic headache
This will try Mulligan mobilization and myofascial release, each with a home exercise program, to see which helps adults aged 18–65 who have had cervicogenic (neck-origin) headache for at least three months.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.