Clinical trial No longer in our active list Interventional Ages 18 to 67

Chiropractic spinal manipulation for headaches

Official title: Chiropractic Spinal Manipulation for Cervicogenic and Tension-type Headache: a Pilot and Feasibility Study

Run by Real Centro Universitario Maria Cristina · NCT05240547 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study is testing if chiropractic spinal manipulation can help reduce the intensity and frequency of chronic headaches in adults who have been suffering from them for at least three months.

Quick facts

Study typeInterventional
Ages18 Years to 67 Years
SexAll
Enrollment20 (estimated)
SponsorReal Centro Universitario Maria Cristina
Academic / other
Locations1 site (San Lorenzo De El Escorial, Madrid)
Trial IDNCT05240547 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 to 67 with a history of cervicogenic or tension-type headaches occurring at least twice a month for the past three months.

Probably not a fit

Patients with frequent migraine headaches or those with contraindications to spinal manipulation will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot randomized controlled trial evaluates the effectiveness of chiropractic spinal manipulative therapy in treating chronic cervicogenic and tension-type headaches. Participants will receive either active spinal manipulation or a sham treatment over 8 sessions, with outcomes measured at various points throughout the study. The goal is to determine if chiropractic care can significantly reduce headache intensity and frequency compared to placebo. A total of 20 participants aged 18 to 67, experiencing headaches for at least 3 months, will be included in the study.

Why it matters

Potential benefit: If successful, this study could provide an effective non-pharmacological treatment option for patients suffering from chronic headaches.

How similar studies have gone: While there have been studies on chiropractic treatment for headaches, this specific approach focusing on cervicogenic and tension-type headaches is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* At least 2 episodes per month of cervicogenic or tension-type headache for at least 3 months. Diagnoses will be determined by case history and physical examination according to the International Headache Society criteria (3rd Edition)

Exclusion Criteria:

* Not fulfilling the inclusion criteria
* Having received chiropractic treatment in the previous 12 months
* Diagnosis or frequent symptoms of migraine headaches (symptoms present at least once a month) without an overlapping presentation of cervicogenic or tension-type headache.
* Patients with pathologies affecting the nervous system (MS, tumors, past history of stroke...)
* Contraindications to manual therapy, particularly spinal manipulative therapy (cancer, uncontrolled high blood-pressure, severe cardiovascular conditions)
* Past history of cervical spine surgery
* Pregnancy
* Having being diagnosed with a psychiatric conditions, with the exception of depression and anxiety

Where it's running

  • Real Centro Universitario María Cristina
    San Lorenzo De El Escorial, Madrid, Spain
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.